1,3-Propanediol

1,3-Propanediol

SCHEMBL18529217

CC(C)(C)c1cc(C(C)(C)C)c(OP(O)O)c(C(C)(C)C)c1.OCCCO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
VCAM1 P19320 4/20 0.35
NR5A2 O00482 1/20 0.35
NR5A1 Q13285 1/20 0.35
RXRA P19793 5/20 0.32
PPARG P37231 4/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
CYP2C9 P11712 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31
RARG P13631 3/20 0.31
ELANE P08246 1/20 0.30
CD69 Q07108 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5865457 0.89 GABRA1 (0.38) NR5A2NR5A1RXRAPPARGGABRA1
SCHEMBL28542242 0.81 POLB (0.36) NR5A2NR5A1RXRAPPARGGABRA1
SCHEMBL4018841 0.81 HSP90AA1 (0.38) NR5A2NR5A1RXRAPPARGGABRA1
SCHEMBL9278608 0.80 CYP2C19 (0.35) NR5A2NR5A1RXRAPPARGGABRA1
SCHEMBL2951542 0.79 NR5A2 (0.36) NR5A2NR5A1RXRAPPARG
Catechol SCHEMBL9355747 0.79 ALDH1A1 (0.44) GABRA1GABRB2CYP1A2CYP3A4CYP2C9
SCHEMBL27567436 0.79 NR5A2 (0.37) NR5A2NR5A1RXRAPPARGCYP1A2
SCHEMBL11421838 0.78 GABRA1 (0.38) NR5A2NR5A1RXRAPPARGGABRA1
SCHEMBL27585599 0.78 CYP2C19 (0.33) NR5A2NR5A1RXRAPPARGCYP1A2
SCHEMBL11431393 0.77 GABRA1 (0.37) RXRAPPARGGABRA1GABRB2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017029278-A1 POLYOLEFIN COMPOSITIONS CONTAINING HIGH CONCENTRATIONS OF REINFORCING FIBERS AND METHODS OF PREPARATION TRINSEO EUROPE GMBH (CH) 2017-02-23 WO disclosed