Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23280210 | 0.63 | SMN1; SMN2 (0.32) | SMN1; SMN2 | |
| SCHEMBL24619980 | 0.61 | KDM4E (0.33) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL27831386 | 0.59 | — | — | |
| SCHEMBL21814427 | 0.58 | ALDH1A1 (0.44) | APAF1ALDH1A1SMN1; SMN2 | |
| SCHEMBL39272 | 0.58 | ALDH1A1 (0.50) | APAF1ALDH1A1 | |
| SCHEMBL3370162 | 0.57 | — | — | |
| SCHEMBL181559 | 0.57 | MAPT (0.52) | ALDH1A1 | |
| SCHEMBL7178297 | 0.57 | LMNA (0.31) | — | |
| SCHEMBL1161081 | 0.56 | IDO1 (0.49) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL1485771 | 0.56 | MAPT (0.36) | APAF1ALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017031276-A1 | METHODS OF PROVIDING NEUROPROTECTIVE THERAPY RELATED TO ADMINISTERING AN ESTROGEN RECEPTOR BETA LIGAND | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-23 | — | — | WO | disclosed |