Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | PDE9A | O76083 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.41 |
| ▸ | GABRD | O14764 | 1/20 | 0.41 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.41 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.41 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.41 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27910999 | 0.77 | KCNMA1 (0.43) | KCNMA1ALDH1A1GPR3HSD17B10PDE9A | |
| SCHEMBL17185603 | 0.74 | PDE9A (0.47) | ALDH1A1GPR3HSD17B10PDE9AMAPT | |
| SCHEMBL2464667 | 0.72 | PDE9A (0.49) | ALDH1A1GPR3HSD17B10PDE9AMAPT | |
| SCHEMBL3676401 | 0.72 | AHR (0.57) | ALDH1A1GPR3HSD17B10PDE9AMAPT | |
| SCHEMBL29635217 | 0.72 | PDE9A (0.49) | ALDH1A1GPR3HSD17B10PDE9AMAPT | |
| SCHEMBL5858501 | 0.71 | PLA2G1B (0.59) | ALDH1A1GPR3HSD17B10PDE9AMAPT | |
| SCHEMBL15926509 | 0.71 | PDE9A (0.47) | ALDH1A1GPR3HSD17B10PDE9AMAPT | |
| SCHEMBL1514832 | 0.71 | PDE9A (0.47) | ALDH1A1GPR3HSD17B10PDE9AMAPT | |
| SCHEMBL25926841 | 0.71 | PDE9A (0.47) | ALDH1A1GPR3HSD17B10PDE9AMAPT | |
| SCHEMBL25929859 | 0.71 | PDE9A (0.47) | ALDH1A1GPR3HSD17B10PDE9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017031276-A1 | METHODS OF PROVIDING NEUROPROTECTIVE THERAPY RELATED TO ADMINISTERING AN ESTROGEN RECEPTOR BETA LIGAND | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2017-02-23 | — | — | WO | disclosed |