Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 12/20 | 0.55 |
| ▸ | KIFC1 | Q9BW19 | 7/20 | 0.39 |
| ▸ | KISS1R | Q969F8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3215617 | 0.94 | GPR52 (0.60) | GPR52KISS1R | |
| SCHEMBL3196491 | 0.89 | GPR52 (0.52) | GPR52 | |
| SCHEMBL1858447 | 0.85 | GPR52 (0.49) | GPR52 | |
| SCHEMBL3208882 | 0.85 | GPR52 (0.73) | GPR52 | |
| SCHEMBL3211306 | 0.85 | GPR52 (0.60) | GPR52KISS1R | |
| SCHEMBL1850527 | 0.83 | GPR52 (0.61) | GPR52KISS1R | |
| SCHEMBL1850789 | 0.81 | GPR52 (0.53) | GPR52 | |
| SCHEMBL1852650 | 0.80 | GPR52 (0.68) | GPR52KIFC1 | |
| SCHEMBL1851150 | 0.79 | GPR52 (0.81) | GPR52 | |
| SCHEMBL1853198 | 0.78 | GPR52 (0.54) | GPR52 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |