Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | BRAF | P15056 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.35 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3196491 | 0.96 | GPR52 (0.52) | GPR52NPC1BRAFTP53POLB | |
| SCHEMBL1850740 | 0.92 | GPR52 (0.49) | GPR52NPC1TP53POLBHPGD | |
| SCHEMBL1854655 | 0.89 | GPR52 (0.51) | GPR52TP53POLBHPGDS1PR5 | |
| SCHEMBL1850789 | 0.87 | GPR52 (0.53) | GPR52NPC1TP53POLBHPGD | |
| SCHEMBL1853149 | 0.85 | GPR52 (0.55) | GPR52 | |
| SCHEMBL1847859 | 0.85 | GPR52 (0.46) | GPR52NPC1TP53POLBHPGD | |
| SCHEMBL1853198 | 0.85 | GPR52 (0.54) | GPR52TP53POLBHPGDS1PR5 | |
| SCHEMBL1855603 | 0.85 | GPR52 (0.51) | GPR52NPC1TP53POLBHPGD | |
| SCHEMBL1851998 | 0.84 | GPR52 (0.65) | GPR52NPC1TP53POLBHPGD | |
| SCHEMBL1855969 | 0.84 | GPR52 (0.45) | GPR52NPC1BRAFTP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |