Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2736125 | 0.86 | ALDH1A1 (0.35) | ALDH1A1TRPV1MAPTSMN1; SMN2LMNA | |
| SCHEMBL18531992 | 0.81 | ALDH1A1 (0.36) | ALDH1A1TRPV1MAPTSMN1; SMN2KDM4E | |
| SCHEMBL18532049 | 0.80 | — | — | |
| SCHEMBL2736128 | 0.78 | GAA (0.31) | ALDH1A1 | |
| SCHEMBL2760081 | 0.73 | ALDH1A1 (0.33) | ALDH1A1MAPTSMN1; SMN2KDM4ETHRB | |
| SCHEMBL18531984 | 0.73 | ALDH1A1 (0.31) | ALDH1A1TRPV1 | |
| SCHEMBL19861658 | 0.72 | TRPV1 (0.38) | ALDH1A1TRPV1 | |
| SCHEMBL18531937 | 0.68 | ACACB (0.38) | MAPTSMN1; SMN2KDM4ETHRBALOX15 | |
| SCHEMBL2760151 | 0.67 | GAA (0.30) | — | |
| SCHEMBL14435659 | 0.66 | TRPV1 (0.44) | ALDH1A1TRPV1MAPTSMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9575080-B2 | — | — | 2017-02-21 | — | — | US | disclosed |