Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.37 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.37 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.37 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.37 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.37 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | DRD3 | P35462 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4401773 | 0.82 | TRPV1 (0.44) | TRPV1ALDH1A1HDAC7HDAC8HDAC6 | |
| SCHEMBL27558794 | 0.80 | SMN1; SMN2 (0.49) | ALDH1A1TSHRCYP3A4KDM4ESMN1; SMN2 | |
| SCHEMBL13932519 | 0.76 | — | — | |
| SCHEMBL8435514 | 0.76 | — | — | |
| SCHEMBL8142982 | 0.76 | — | — | |
| SCHEMBL14818668 | 0.76 | METAP1 (0.38) | TRPV1ALDH1A1HDAC7HDAC8HDAC6 | |
| SCHEMBL26658367 | 0.75 | ALDH1A1 (0.33) | TRPV1ALDH1A1HDAC7HDAC8HDAC6 | |
| SCHEMBL14157901 | 0.74 | TRPV1 (0.46) | TRPV1ALDH1A1TDP1NFKB1KDM4E | |
| SCHEMBL20228901 | 0.74 | TRPV1 (0.39) | TRPV1ALDH1A1HDAC7HDAC8HDAC6 | |
| SCHEMBL10033481 | 0.73 | TAS1R3 (0.50) | HDAC7HDAC8HDAC6HDAC9HDAC5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007095218-A1 | INTRAVENOUS ANTIVIRAL TREATMENTS | BIOCRYST PHARMACEUTICALS, INC. (US) | 2007-08-23 | — | — | WO | disclosed |