Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.57 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.57 |
| ▸ | CA12 | O43570 | 2/20 | 0.50 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA3 | P07451 | 2/20 | 0.50 |
| ▸ | CA4 | P22748 | 2/20 | 0.50 |
| ▸ | CA6 | P23280 | 2/20 | 0.50 |
| ▸ | CA5A | P35218 | 2/20 | 0.50 |
| ▸ | CA7 | P43166 | 2/20 | 0.50 |
| ▸ | CA9 | Q16790 | 2/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | BLM | P54132 | 2/20 | 0.50 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.48 |
| ▸ | GSR | P00390 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL148994 | 0.97 | TRPV1 (0.52) | TRPV1TRPA1CA12CA1CA2 | |
| SCHEMBL4395969 | 0.89 | TRPV1 (0.48) | TRPV1TRPA1CA12CA1CA2 | |
| SCHEMBL13387147 | 0.87 | TRPV1 (0.48) | TRPV1TRPA1CA12CA1CA2 | |
| SCHEMBL20381254 | 0.84 | TRPV1 (0.61) | TRPV1TRPA1CA12CA1CA2 | |
| SCHEMBL28621886 | 0.84 | TRPV1 (0.61) | TRPV1TRPA1CA12CA1CA2 | |
| SCHEMBL9189977 | 0.84 | TRPV1 (0.54) | TRPV1TRPA1CA12CA1CA2 | |
| SCHEMBL9325038 | 0.84 | TRPV1 (0.54) | TRPV1TRPA1CA12CA1CA2 | |
| SCHEMBL29152441 | 0.84 | TRPV1 (0.61) | TRPV1TRPA1CA12CA1CA2 | |
| SCHEMBL21581157 | 0.84 | TRPV1 (0.48) | TRPV1TRPA1LMNABLMDNM1 | |
| SCHEMBL13624933 | 0.81 | DNM1 (0.50) | TRPV1TRPA1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3337794-B1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-07-21 | — | — | EP | disclosed |
| EP-3133066-A1 | HYDROPHILIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |