Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.48 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | BLM | P54132 | 2/20 | 0.43 |
| ▸ | GMNN | O75496 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | MTOR | P42345 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | UBE2N | P61088 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6004665 | 0.90 | TRPV1 (0.40) | TRPV1TRPA1CYP2D6SPHK1LMNA | |
| SCHEMBL19159678 | 0.90 | TRPV1 (0.40) | TRPV1TRPA1CYP2D6SPHK1LMNA | |
| SCHEMBL18533822 | 0.89 | TRPV1 (0.57) | TRPV1TRPA1CYP2D6SPHK1LMNA | |
| SCHEMBL148994 | 0.87 | TRPV1 (0.52) | TRPV1TRPA1CYP2D6SPHK1LMNA | |
| SCHEMBL10564366 | 0.79 | LMNA (0.41) | TRPV1TRPA1CYP2D6SPHK1LMNA | |
| SCHEMBL2985499 | 0.79 | LMNA (0.41) | TRPV1TRPA1CYP2D6SPHK1LMNA | |
| SCHEMBL3168782 | 0.79 | LMNA (0.41) | TRPV1TRPA1CYP2D6SPHK1LMNA | |
| SCHEMBL891846 | 0.79 | LMNA (0.41) | TRPV1TRPA1CYP2D6SPHK1LMNA | |
| SCHEMBL6448213 | 0.79 | LMNA (0.41) | TRPV1TRPA1CYP2D6SPHK1LMNA | |
| SCHEMBL11640496 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090216117-A1 | NOVEL METHOD OF USING TRIACETIN AND AUXILIARY AGENT FOR ULTRASONIC DIAGNOSTIC EXAMINATION | SHINSHU UNIVERSITY (JP) | 2009-08-27 | — | — | US | disclosed |