Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 5/20 | 0.61 |
| ▸ | KIFC1 | Q9BW19 | 8/20 | 0.45 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.40 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1850570 | 0.91 | GPR52 (0.69) | GPR52KIFC1MEN1NPC1RAB9A | |
| SCHEMBL1854619 | 0.91 | GPR52 (0.68) | GPR52S1PR4S1PR5 | |
| SCHEMBL1848922 | 0.88 | GPR52 (0.46) | GPR52KIFC1S1PR4S1PR5 | |
| SCHEMBL1851881 | 0.85 | GPR52 (0.66) | GPR52KIFC1MEN1NPC1RAB9A | |
| SCHEMBL1856500 | 0.84 | GPR52 (0.66) | GPR52KIFC1S1PR4S1PR5MEN1 | |
| SCHEMBL3221341 | 0.80 | GPR52 (0.77) | GPR52S1PR4S1PR5 | |
| SCHEMBL1853467 | 0.80 | PRF1 (0.48) | S1PR4S1PR5NPC1RAB9A | |
| SCHEMBL1847859 | 0.79 | GPR52 (0.46) | GPR52S1PR4S1PR5NPC1RAB9A | |
| SCHEMBL1850137 | 0.79 | GPR52 (0.69) | GPR52KIFC1S1PR4S1PR5NPC1 | |
| SCHEMBL1850159 | 0.78 | GPR52 (0.54) | GPR52S1PR4S1PR5NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |