Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR52 | Q9Y2T5 | 8/20 | 0.66 |
| ▸ | S1PR4 | O95977 | 6/20 | 0.48 |
| ▸ | S1PR5 | Q9H228 | 6/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | KIFC1 | Q9BW19 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3210261 | 0.93 | GPR52 (0.75) | GPR52S1PR4S1PR5MAPTHTT | |
| SCHEMBL1854516 | 0.91 | S1PR4 (0.56) | GPR52S1PR4S1PR5MEN1MAPT | |
| SCHEMBL1853392 | 0.84 | GPR52 (0.61) | GPR52S1PR4S1PR5MEN1KMT2A | |
| SCHEMBL3198611 | 0.84 | GPR52 (0.76) | GPR52S1PR4S1PR5MRGPRX4 | |
| SCHEMBL1854277 | 0.80 | S1PR5 (0.63) | GPR52S1PR4S1PR5 | |
| SCHEMBL1852605 | 0.80 | GPR52 (1.00) | GPR52S1PR4S1PR5MRGPRX4 | |
| SCHEMBL3219750 | 0.80 | GPR52 (0.74) | GPR52S1PR4S1PR5MRGPRX4 | |
| SCHEMBL1854351 | 0.79 | GPR52 (0.85) | GPR52S1PR4S1PR5MRGPRX4 | |
| SCHEMBL1850570 | 0.79 | GPR52 (0.69) | GPR52MEN1KMT2AKIFC1 | |
| SCHEMBL1858166 | 0.78 | GPR52 (0.56) | GPR52S1PR4S1PR5MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323978-A1 | AMIDE COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2011-05-25 | — | — | EP | disclosed |
| WO-2010018874-A1 | AMIDE COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2010-02-18 | — | — | WO | disclosed |