Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PDK2 | Q15119 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | ICMT | O60725 | 1/20 | 0.32 |
| ▸ | PGR | P06401 | 1/20 | 0.32 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.32 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20707239 | 0.99 | LMNA (0.40) | LMNANPSR1ESR1ESR2PDK2 | |
| SCHEMBL12978440 | 0.94 | ESR1 (0.43) | LMNANPSR1ESR1ESR2PDK2 | |
| SCHEMBL10031186 | 0.92 | ESR1 (0.40) | LMNAESR1ESR2PDK2MAPT | |
| SCHEMBL12978467 | 0.91 | PDK2 (0.40) | LMNANPSR1ESR1ESR2PDK2 | |
| SCHEMBL14559298 | 0.91 | ESR1 (0.41) | LMNANPSR1ESR1ESR2PDK2 | |
| SCHEMBL10031193 | 0.90 | ESR1 (0.39) | LMNANPSR1ESR1ESR2PDK2 | |
| SCHEMBL23079462 | 0.89 | KDM4E (0.40) | LMNAESR1ESR2PDK2MAPT | |
| SCHEMBL3468560 | 0.89 | KDM4E (0.40) | LMNAESR1ESR2PDK2MAPT | |
| SCHEMBL22403503 | 0.89 | KDM4E (0.40) | LMNAESR1ESR2PDK2MAPT | |
| SCHEMBL23079446 | 0.89 | KDM4E (0.40) | LMNAESR1ESR2PDK2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133665-B1 | ORGANIC ELECTROLUMINESCENT DEVICE | HODOGAYA CHEMICAL CO LTD (JP) | 2020-03-04 | — | — | EP | disclosed |
| EP-3133665-A1 | ORGANIC ELECTROLUMINESCENT DEVICE | Hodogaya Chemical Co., Ltd. (JP) | 2017-02-22 | — | — | EP | disclosed |