SCHEMBL20707239

SCHEMBL20707239

Cc1cccc(C2(c3cccc(N(c4ccc(-c5ccccc5)cc4)c4ccc(-c5ccccc5)cc4)c3)c3ccccc3-c3ccccc32)c1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.40
NPSR1 Q6W5P4 1/20 0.40
PDK2 Q15119 6/20 0.40
ESR1 P03372 1/20 0.40
ESR2 Q92731 1/20 0.40
PGR P06401 1/20 0.33
HSD17B1 P14061 1/20 0.33
HSD17B2 P37059 1/20 0.33
MAPT P10636 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.33
OPRK1 P41145 1/20 0.33
KMT2A Q03164 1/20 0.33
POLB P06746 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
ENPP3 O14638 1/20 0.32
EPHX1 P07099 1/20 0.32
ICMT O60725 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18533947 0.99 LMNA (0.41) LMNANPSR1PDK2ESR1ESR2
SCHEMBL12978440 0.95 ESR1 (0.43) LMNANPSR1PDK2ESR1ESR2
SCHEMBL12978467 0.92 PDK2 (0.40) LMNANPSR1PDK2ESR1ESR2
SCHEMBL10031193 0.92 ESR1 (0.39) LMNANPSR1PDK2ESR1ESR2
SCHEMBL23079462 0.91 KDM4E (0.40) LMNAPDK2ESR1ESR2MAPT
SCHEMBL3468560 0.91 KDM4E (0.40) LMNAPDK2ESR1ESR2MAPT
SCHEMBL22403503 0.91 KDM4E (0.40) LMNAPDK2ESR1ESR2MAPT
SCHEMBL23079446 0.91 KDM4E (0.40) LMNAPDK2ESR1ESR2MAPT
SCHEMBL18287507 0.91 KDM4E (0.40) LMNAPDK2ESR1ESR2MAPT
SCHEMBL19567736 0.91 ESR1 (0.38) LMNANPSR1PDK2ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3133665-B1 ORGANIC ELECTROLUMINESCENT DEVICE HODOGAYA CHEMICAL CO LTD (JP) 2020-03-04 EP disclosed
EP-2704225-B1 ORGANIC ELECTROLUMINESCENT ELEMENT HODOGAYA CHEMICAL CO LTD (JP) 2019-02-06 EP disclosed