SCHEMBL18534253

SCHEMBL18534253

COC(=O)C(C)(CN(C)C)N(C)C

nearest known ligand 0.35

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
DGAT1 O75907 1/20 0.35
CYP1A2 P05177 1/20 0.31
CYP2D6 P10635 1/20 0.31
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22874332 0.80 DGAT1 (0.37) DGAT1MEN1KMT2A
SCHEMBL18026356 0.80 DGAT1 (0.37) DGAT1MEN1KMT2A
SCHEMBL22874325 0.80 DGAT1 (0.37) DGAT1MEN1KMT2A
SCHEMBL12555846 0.74 CYP2C19 (0.35) DGAT1CYP2C19
SCHEMBL12555921 0.74 CYP2C19 (0.35) DGAT1CYP2C19
SCHEMBL12555893 0.74 CYP2C19 (0.35) DGAT1CYP2C19
SCHEMBL31405859 0.72 DGAT1 (0.31) DGAT1
SCHEMBL18026357 0.72 DGAT1 (0.31) DGAT1
SCHEMBL12555911 0.71 ALDH1A1 (0.37) DGAT1
SCHEMBL12555823 0.71 ALDH1A1 (0.37) DGAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3133126-A1 COLORING COMPOSITION, CURED FILM, COLOR FILTER, METHOD FOR PRODUCING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, IMAGE DISPLAY DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, DYE AND METHOD FOR PRODUCING DYE Fujifilm Corporation (JP) 2017-02-22 EP disclosed