Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPL | P06858 | 8/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 8/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15585595 | 1.00 | LPL (0.36) | LPLLIPGDGAT1SNCA | |
| SCHEMBL14655962 | 0.84 | LIPG (0.38) | LPLLIPGDGAT1 | |
| SCHEMBL15586249 | 0.82 | — | — | |
| SCHEMBL15362840 | 0.82 | LPL (0.37) | LPLLIPGDGAT1 | |
| SCHEMBL18727540 | 0.81 | LPL (0.36) | LPLLIPGDGAT1SNCA | |
| SCHEMBL2372832 | 0.80 | USP30 (0.40) | LPLLIPGDGAT1 | |
| SCHEMBL16577461 | 0.80 | USP30 (0.40) | LPLLIPGDGAT1 | |
| SCHEMBL21334152 | 0.80 | VHL (0.33) | LPLLIPG | |
| SCHEMBL17212628 | 0.80 | USP30 (0.40) | LPLLIPGDGAT1 | |
| SCHEMBL2372829 | 0.80 | USP30 (0.40) | LPLLIPGDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2773634-B1 | ROD-LIKE HEPATITIS C VIRUS INHIBITORS CONTAINING THE FRAGEMENT {2-[4-(BIPHENYL-4-YL)-1H-IMIDAZO-2-YL]PYRROLIDINE-1-CARBONLYMETHYL}AMINE | THERAVANCE BIOPHARMA R&D IP LLC (US) | 2018-06-06 | — | — | EP | disclosed |