Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | GLA | P06280 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA2 | P00918 | 2/20 | 0.38 |
| ▸ | CA4 | P22748 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 2/20 | 0.38 |
| ▸ | CA3 | P07451 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18535468 | 0.86 | RAB9A (0.39) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL18535514 | 0.85 | KLK7 (0.36) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL18535452 | 0.84 | MAOB (0.40) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL18535500 | 0.83 | ACHE (0.40) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL22590810 | 0.83 | MAOB (0.33) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL18583383 | 0.82 | MAOB (0.35) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL18535462 | 0.82 | KDM4E (0.38) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL22590837 | 0.82 | MAPT (0.34) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL23893581 | 0.81 | RAB9A (0.34) | MAOBKDM4EGLAGAAHPGD | |
| SCHEMBL18583374 | 0.81 | MAOB (0.35) | MAOBKDM4EGLAGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3133065-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | Merck Patent GmbH (DE) | 2017-02-22 | — | — | EP | disclosed |