SCHEMBL18535906

SCHEMBL18535906

C=Cc1c(/C=C\C)ccc(=O)n1C

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.32
BRD4 O60885 1/20 0.32
BRPF1 P55201 1/20 0.32
CA9 Q16790 1/20 0.32
KAT2B Q92831 1/20 0.32
BRD9 Q9H8M2 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18184622 0.72
SCHEMBL31667098 0.72 BRPF1 (0.34) CA12BRD4BRPF1CA9KAT2B
SCHEMBL13376898 0.70 BRPF1 (0.33) CA12BRD4BRPF1CA9KAT2B
SCHEMBL18323704 0.70 HMGCR (0.31)
SCHEMBL23346803 0.70
SCHEMBL14463965 0.69 NOTUM (0.33)
SCHEMBL20517578 0.68 BRPF1 (0.34) CA12BRD4BRPF1CA9KAT2B
SCHEMBL14341095 0.68 BRPF1 (0.39) CA12BRD4BRPF1CA9KAT2B
SCHEMBL22729976 0.67
SCHEMBL21782826 0.67 LMNA (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3133444-A1 CHEMICALLY AMPLIFIED RESIST MATERIAL, PATTERN-FORMING METHOD, COMPOUND, AND PRODUCTION METHOD OF COMPOUND OSAKA UNIVERSITY (JP) 2017-02-22 EP disclosed