Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR2 | O43614 | 2/20 | 0.30 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15519213 | 0.73 | CA2 (0.38) | — | |
| SCHEMBL15509016 | 0.73 | CA2 (0.38) | — | |
| SCHEMBL16599580 | 0.67 | ALDH1A1 (0.50) | — | |
| SCHEMBL12073058 | 0.62 | HCRTR1 (0.33) | HCRTR2HCRTR1 | |
| SCHEMBL14936023 | 0.62 | HCRTR1 (0.33) | HCRTR2HCRTR1 | |
| SCHEMBL29990890 | 0.61 | IDH1 (0.36) | — | |
| SCHEMBL17236191 | 0.61 | CA2 (0.32) | — | |
| SCHEMBL18946789 | 0.59 | TMEM97 (0.31) | — | |
| SCHEMBL15514647 | 0.59 | CCNE1 (0.42) | — | |
| SCHEMBL24288138 | 0.58 | MAPK8 (0.47) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2909212-B1 | SUBSTITUTED 1,4-DIHYDROPYRAZOLO[4,3-B]INDOLES | TAKEDA PHARMACEUTICALS CO (JP) | 2017-02-22 | — | — | EP | disclosed |