SCHEMBL18536621

SCHEMBL18536621

CON=C1C(=O)N(C)C(=O)N(C)C1=O

nearest known ligand 0.30

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30
TTR P02766 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3285696 0.70 MEN1 (0.32) MEN1KMT2A
SCHEMBL133474 0.69 GSK3A (0.39) MEN1KMT2ATTR
SCHEMBL6837156 0.65 MIF (0.35)
SCHEMBL530530 0.64 CASP3 (0.40) MEN1KMT2ATTR
Water SCHEMBL9841308 0.62 CASP3 (0.39) MEN1KMT2ATTR
SCHEMBL24599365 0.60 MEN1 (0.36) MEN1KMT2A
SCHEMBL6338046 0.60 ADRA2C (0.32) MEN1KMT2A
SCHEMBL6614354 0.60 ADRA2C (0.32) MEN1KMT2A
SCHEMBL12220326 0.60 ADRA2C (0.32) MEN1KMT2A
SCHEMBL6836947 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3133062-A1 PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL AGENT Zaklady Farmaceutyczne Polpharma SA (PL) 2017-02-22 EP disclosed