SCHEMBL1853697

SCHEMBL1853697

O=P(Oc1c[nH]c2ccccc12)(Oc1c[nH]c2ccccc12)Oc1c[nH]c2ccccc12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.54
PBRM1 Q86U86 1/20 0.46
GPR84 Q9NQS5 2/20 0.44
IMPDH2 P12268 2/20 0.44
CYP2A6 P11509 1/20 0.44
ATM Q13315 2/20 0.44
MEN1 O00255 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
AHR P35869 1/20 0.42
KMT2A Q03164 1/20 0.42
TDP1 Q9NUW8 1/20 0.42
NR4A2 P43354 2/20 0.42
CREBBP Q92793 1/20 0.42
ALDH1A1 P00352 1/20 0.42
PRKD3 O94806 1/20 0.41
CCNB2 O95067 1/20 0.41
CCNE2 O96020 1/20 0.41
ABL1 P00519 1/20 0.41
PRKCG P05129 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL460942 0.85 SLC22A6 (0.51) SLC22A6PBRM1GPR84IMPDH2CYP2A6
SCHEMBL540158 0.85 SLC22A6 (0.56) SLC22A6PBRM1GPR84IMPDH2CYP2A6
SCHEMBL5638234 0.85 SLC22A6 (0.51) SLC22A6PBRM1GPR84IMPDH2CYP2A6
SCHEMBL31034497 0.85 SLC22A6 (0.56) SLC22A6PBRM1GPR84IMPDH2CYP2A6
SCHEMBL29769232 0.85 SLC22A6 (0.51) SLC22A6PBRM1GPR84IMPDH2CYP2A6
SCHEMBL7159281 0.84 SLC22A6 (0.44) SLC22A6PBRM1GPR84IMPDH2CYP2A6
SCHEMBL27808262 0.82 SLC22A6 (0.57) SLC22A6PBRM1GPR84ATMMEN1
SCHEMBL3279763 0.80 SLC22A6 (0.50) SLC22A6PBRM1GPR84IMPDH2CYP2A6
SCHEMBL28034562 0.80 SLC22A6 (0.50) SLC22A6PBRM1GPR84IMPDH2CYP2A6
SCHEMBL11439863 0.80 SLC22A6 (0.50) SLC22A6PBRM1GPR84IMPDH2CYP2A6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 142 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0476930-B1 Enzyme assays SANKYO CO (JP) 1997-11-12 EP claimed
EP-0369362-B1 Substrate composition for alkaline phosphatase and method for assay using same BECTON DICKINSON CO (US) 1995-02-15 EP claimed
US-5093231-A Levamisole BECTON, DICKINSON AND COMPANY (US) 1992-03-03 US claimed
EP-0369362-A2 Substrate composition for alkaline phosphatase and method for assay using same Becton, Dickinson and Company (US) 1990-05-23 EP claimed
EP-0269979-A2 Analytical element for measuring alkaline phosphatase KONICA CORPORATION (JP) 1988-06-08 EP claimed
EP-0248892-A1 PARTICLE-BOUND BINDING COMPONENT IMMUNOASSAY Murex Corporation (US) 1987-12-16 EP claimed
WO-1987003690-A1 PARTICLE-BOUND BINDING COMPONENT IMMUNOASSAY MUREX CORPORATION (US) 1987-06-18 WO claimed
US-4030995-A Alkaline phosphatase isoenzyme determination SIGMA CHEMICAL COMPANY (US) 1977-06-21 US claimed
JP-2207800-A None JP disclosed
JP-3083599-A None JP disclosed
US-20260036584-A1 COMPOSITIONS AND METHODS TO DETECT GASTROINTESTINAL DISEASE THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIV AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2026-02-05 US disclosed
EP-3295173-B1 COMPOSITIONS AND METHODS FOR SIMULTANEOUS INACTIVATION OF ALKALINE PHOSPHATASE AND PEROXIDASE ENZYMES DURING AUTOMATED MULTIPLEX TISSUE STAINING ASSAYS VENTANA MED SYST INC (US) 2025-11-05 EP disclosed
US-20250133130-A1 COMPOSITIONS AND METHODS FOR DETECTING PROTEINOPATHIES UNIV LOUISIANA STATE (US) 2025-04-24 US disclosed
US-12282019-B2 Compositions and methods to detect gastrointestinal disease THE BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE (US) 2025-04-22 US disclosed
EP-0172153-B1 POLYNUCLEOTIDE HYBRIDIZATION PROBES SMITHKLINE BECKMAN CORPORATION (US) 1989-08-09 EP disclosed
US-4840892-A Polynucleotide hybridization probes SMITHKLINE BECKMAN CORPORATION (US) 1989-06-20 US disclosed
EP-0269979-A2 Analytical element for measuring alkaline phosphatase KONICA CORPORATION (JP) 1988-06-08 EP disclosed
WO-1987007384-A1 ENZYME IMMUNOASSAY DEVICE QUIDEL (US) 1987-12-03 WO disclosed
EP-0172153-A1 Polynucleotide hybridization probes SMITHKLINE BECKMAN CORPORATION (US) 1986-02-19 EP disclosed
US-4030995-A Alkaline phosphatase isoenzyme determination SIGMA CHEMICAL COMPANY (US) 1977-06-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260036584-A1 COMPOSITIONS AND METHODS TO DETECT GASTROINTESTINAL DISEASE SI, FABP2, VIP SLC22A6 831/4885PBRM1 4469/4885GPR84 3355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.