SCHEMBL540158

SCHEMBL540158

O=P(O)(O)Oc1c[nH]c2ccccc12

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC22A6 Q4U2R8 2/20 0.56
PBRM1 Q86U86 1/20 0.47
GPR84 Q9NQS5 1/20 0.46
HTR2A P28223 2/20 0.45
HTR1A P08908 1/20 0.45
HTR2C P28335 1/20 0.45
HTR2B P41595 1/20 0.45
INPPL1 O15357 3/20 0.44
INPP5A Q14642 3/20 0.44
INPP5B P32019 2/20 0.44
NR4A2 P43354 1/20 0.44
CREBBP Q92793 1/20 0.44
ALDH1A1 P00352 2/20 0.43
SRC P12931 2/20 0.43
KDM4E B2RXH2 1/20 0.43
USP2 O75604 1/20 0.43
HPGD P15428 1/20 0.43
PDE3A Q14432 1/20 0.43
HSD17B10 Q99714 1/20 0.43
ATM Q13315 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31034497 1.00 SLC22A6 (0.56) SLC22A6PBRM1GPR84HTR2AHTR1A
Glycerin SCHEMBL7561723 0.88 SLC22A6 (0.46) SLC22A6PBRM1GPR84HTR2AHTR1A
SCHEMBL27808262 0.86 SLC22A6 (0.57) SLC22A6PBRM1GPR84NR4A2CREBBP
SCHEMBL30903953 0.86 SLC22A6 (0.47) SLC22A6PBRM1HTR2AHTR1AHTR2C
O-Tolylamine SCHEMBL7799079 0.86 SLC22A6 (0.47) SLC22A6PBRM1HTR2AHTR1AHTR2C
SCHEMBL7800278 0.86 SLC22A6 (0.47) SLC22A6PBRM1HTR2AHTR1AHTR2C
SCHEMBL458847 0.86 SLC22A6 (0.47) SLC22A6PBRM1HTR2AHTR1AHTR2C
O-Tolylamine SCHEMBL6636539 0.86 SLC22A6 (0.47) SLC22A6PBRM1HTR2AHTR1AHTR2C
SCHEMBL1853697 0.85 SLC22A6 (0.54) SLC22A6PBRM1GPR84NR4A2CREBBP
SCHEMBL463226 0.85 SLC22A6 (0.46) SLC22A6PBRM1HTR2AHTR1AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114133551-B Pyrimidine polyether and preparation method and application thereof 万华化学集团股份有限公司 2023-05-30 CN claimed
CN-114133551-A Pyrimidyl polyether and preparation method and application thereof 万华化学集团股份有限公司 2022-03-04 CN claimed
CN-105759054-B A kind of ELISPOT detection kits for being used to detect B.abortus disease 扬州大学 2017-10-20 CN claimed
CN-101535496-B Genetically engineered biological indicator AMERICAN STERILIZER CO. (US) 2015-12-02 CN claimed
CN-1973048-B Terminal-phosphate-labeled nucleotides and methods of use GE HEALTHCARE BIO SCIENCES 2015-06-03 CN claimed
US-20150140569-A1 ELISpot diagnostic kit for neuromyelitis optica and its application Xu, Jun (CN) 2015-05-21 US claimed
CN-101384729-B Solid phase sequencing AMERSHAM BIOSCIENCES CORP 2014-09-10 CN claimed
CN-101541944-B Sterilization indicator AMERICAN STERILIZER CO 2013-05-22 CN claimed
EP-2186906-B1 Medium for detecting and differentiating vancomycin-resistant enterococci OXOID LTD (GB) 2012-07-25 EP claimed
CN-101541944-A Sterilization indicator AMERICAN STERILIZER CO (US) 2009-09-23 CN claimed
EP-1330542-A2 FAST METHOD FOR DETECTING ORGANISMS IN A SAMPLE Skuld-Tech S.A.R.L. (FR) 2003-07-30 EP claimed
WO-2002029096-A2 FAST METHOD FOR DETECTING ORGANISMS IN A SAMPLE SKULD-TECH S.A.R.L. (FR) 2002-04-11 WO claimed
EP-0476930-B1 Enzyme assays SANKYO CO (JP) 1997-11-12 EP claimed
EP-0369362-B1 Substrate composition for alkaline phosphatase and method for assay using same BECTON DICKINSON CO (US) 1995-02-15 EP claimed
US-5093231-A Levamisole BECTON, DICKINSON AND COMPANY (US) 1992-03-03 US claimed
EP-0369362-A2 Substrate composition for alkaline phosphatase and method for assay using same Becton, Dickinson and Company (US) 1990-05-23 EP claimed
EP-0269979-A2 Analytical element for measuring alkaline phosphatase KONICA CORPORATION (JP) 1988-06-08 EP claimed
EP-0248892-A1 PARTICLE-BOUND BINDING COMPONENT IMMUNOASSAY Murex Corporation (US) 1987-12-16 EP claimed
WO-1987003690-A1 PARTICLE-BOUND BINDING COMPONENT IMMUNOASSAY MUREX CORPORATION (US) 1987-06-18 WO claimed
US-4030995-A Alkaline phosphatase isoenzyme determination SIGMA CHEMICAL COMPANY (US) 1977-06-21 US claimed