SCHEMBL18537809

SCHEMBL18537809

C=C(C)/C=C/C(C(=O)OCC(C)C)C(C)C

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.47
SMN1; SMN2 Q16637 2/20 0.33
USP2 O75604 1/20 0.33
LMNA P02545 1/20 0.33
CYP3A4 P08684 1/20 0.33
MAPT P10636 1/20 0.33
RECQL P46063 1/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28127347 0.84 ALDH1A1 (0.35) TSHRLMNAALDH1A1HPGD
SCHEMBL18537807 0.80 SMN1; SMN2 (0.38) TSHRSMN1; SMN2ALDH1A1
SCHEMBL18539505 0.75
SCHEMBL18537810 0.74 ALDH1A1 (0.49) LMNAALDH1A1
SCHEMBL16674847 0.74 SLC7A5 (0.36)
SCHEMBL16670214 0.74 SLC7A5 (0.36)
SCHEMBL16670213 0.74 SLC7A5 (0.36)
SCHEMBL18523374 0.70 USP2 (0.40) TSHRSMN1; SMN2USP2LMNACYP3A4
SCHEMBL18523375 0.70 USP2 (0.40) TSHRSMN1; SMN2USP2LMNACYP3A4
SCHEMBL18523389 0.70 USP2 (0.40) TSHRSMN1; SMN2USP2LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106467464-B (E) -2-isopropyl-5-methyl-3, 5-hexadienoic acid ester compound and production method and application thereof 信越化学工业株式会社 2020-12-29 CN disclosed
US-9725400-B2 (E)-2-isopropyl-5-methyl-3,5-hexadienoate compound, method for producing the same, and methods for producing (E)-2-isopropyl-5-methyl-3,5-hexadienol and (E)-2-isopropyl-5-methyl-3,5-hexadienyl carboxylate by using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-08 US disclosed
US-9725400-B2 (E)-2-isopropyl-5-methyl-3,5-hexadienoate compound, method for producing the same, and methods for producing (E)-2-isopropyl-5-methyl-3,5-hexadienol and (E)-2-isopropyl-5-methyl-3,5-hexadienyl carboxylate by using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-08 US disclosed
CN-106467464-A (E) 2 isopropyl 5 methyl 3,5 hexadienoic acid ester compounds and its production method and produce (E) 2 isopropyl 5 methyl 3 using it, 5 hexadienols and the method for (E) 2 isopropyl 5 methyl 3,5 hexadienyl carboxylate 信越化学工业株式会社 2017-03-01 CN disclosed
US-20170050913-A1 (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-23 US disclosed
US-20170050913-A1 (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-02-23 US disclosed
EP-3133053-A1 (E)-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME Shin-Etsu Chemical Co., Ltd. (JP) 2017-02-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170050913-A1 (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOATE COMPOUND, METHOD FOR PRODUCING THE SAME, AND METHODS FOR PRODUCING (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENOL AND (E)-2-ISOPROPYL-5-METHYL-3,5-HEXADIENYL CARBOXYLATE BY USING THE SAME SHBG, GNE, PGRMC2 TSHR 4112/4885SMN1; SMN2 3564/4885USP2 2765/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.