⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1849413 | 0.77 | — | — | |
| SCHEMBL948388 | 0.69 | — | — | |
| SCHEMBL3081144 | 0.65 | — | — | |
| SCHEMBL13573553 | 0.64 | MEN1 (0.33) | — | |
| SCHEMBL1853832 | 0.64 | NAAA (0.30) | — | |
| SCHEMBL7874498 | 0.63 | — | — | |
| SCHEMBL16808726 | 0.63 | — | — | |
| SCHEMBL3612719 | 0.63 | CHRM2 (0.30) | — | |
| SCHEMBL9451858 | 0.63 | MEN1 (0.34) | — | |
| SCHEMBL11194617 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110178001-A1 | PHOSPHONATED RIFAMYCINS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | TARGANTA THERAPEUTICS CORP. (US) | 2011-07-21 | — | — | US | disclosed |
| EP-2324041-A2 | PHOSPHONATED RIFAMYCINS AND USES THEREOF FOR THE PREVENTION AND TREATMENT OF BONE AND JOINT INFECTIONS | Targanta Therapeutics Corp. (US) | 2011-05-25 | — | — | EP | disclosed |