Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 4/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.40 |
| ▸ | BAX | Q07812 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 3/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Diphenylether SCHEMBL22829709 | 0.88 | LTA4H (0.52) | LTA4HTSHRCA4MEN1KMT2A | |
| SCHEMBL25620251 | 0.87 | PTPN1 (0.46) | LTA4HSMN1; SMN2ALDH1A1MAPTACHE | |
| SCHEMBL12925863 | 0.80 | LTA4H (0.57) | LTA4HTSHRMEN1KMT2ANPC1 | |
| SCHEMBL2094797 | 0.79 | LTA4H (0.56) | LTA4HTSHRCA4MEN1KMT2A | |
| SCHEMBL12585926 | 0.79 | PTPN1 (0.42) | SMN1; SMN2ALDH1A1MAPTKDM4EMAPK1 | |
| SCHEMBL18415521 | 0.78 | LTA4H (0.73) | LTA4HTSHRCA4MEN1KMT2A | |
| SCHEMBL17737942 | 0.77 | MAPT (0.39) | LTA4HTSHRMEN1KMT2ANPC1 | |
| SCHEMBL11579139 | 0.77 | LTA4H (0.44) | LTA4HTSHRCA4LMNAL3MBTL1 | |
| SCHEMBL8517685 | 0.77 | LTA4H (0.52) | LTA4HTSHRMEN1KMT2ANPC1 | |
| SCHEMBL14036886 | 0.77 | LTA4H (0.52) | LTA4HTSHRMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828466-B2 | Polyphenylene ether derivative having N-substituted maleimide group, and heat curable resin composition, resin varnish, prepreg, metal-clad laminate, and multilayer printed wiring board using same | HITACHI CHEMICAL COMPANY, LTD (JP) | 2017-11-28 | — | — | US | disclosed |
| US-20170051109-A1 | POLYPHENYLENE ETHER DERIVATIVE HAVING N-SUBSTITUTED MALEIMIDE GROUP, AND HEAT CURABLE RESIN COMPOSITION, RESIN VARNISH, PREPREG, METAL-CLAD LAMINATE, AND MULTILAYER PRINTED WIRING BOARD USING SAME | HITACHI CHEMICAL COMPANY, LTD. (JP) | 2017-02-23 | — | — | US | disclosed |
| CN-100516040-C | Nitrogenous heterocyclic derivative having 2,6-disubstituted styryl | ASTELLAS PHARMA INC KOTOBUKI S (JP) | 2009-07-22 | — | — | CN | disclosed |