SCHEMBL1854

SCHEMBL1854

O=C(Cl)c1ccc(Cl)cc1

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CES2 O00748 3/20 0.65
CES1 P23141 3/20 0.65
TSHR P16473 2/20 0.62
ALOX15 P16050 1/20 0.62
CA1 P00915 2/20 0.59
CA2 P00918 2/20 0.59
MAPK1 P28482 2/20 0.55
L3MBTL1 Q9Y468 2/20 0.55
CYP3A4 P08684 1/20 0.55
ATM Q13315 1/20 0.55
GSK3B P49841 2/20 0.54
SRD5A2 P31213 1/20 0.54
ALDH1A1 P00352 2/20 0.52
LMNA P02545 2/20 0.52
KDM4E B2RXH2 1/20 0.52
MAPT P10636 1/20 0.52
CYP2A6 P11509 1/20 0.47
PTGS2 P35354 1/20 0.46
ERCC5 P28715 1/20 0.46
FEN1 P39748 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5757987 1.00 CES2 (0.65) CES2CES1TSHRALOX15CA1
SCHEMBL1330271 1.00 CES2 (0.65) CES2CES1TSHRALOX15CA1
Bromide SCHEMBL28583978 0.97 CES2 (0.62) CES2CES1TSHRALOX15CA1
Hydrochloric Acid SCHEMBL5565187 0.97 CES2 (0.62) CES2CES1TSHRALOX15CA1
Ammonia Solution, Strong SCHEMBL28864885 0.97 CES2 (0.62) CES2CES1TSHRALOX15CA1
SCHEMBL7349867 0.95 CES2 (0.59) CES2CES1TSHRALOX15CA1
SCHEMBL2902010 0.92 CES2 (0.56) CES2CES1TSHRALOX15CA1
SCHEMBL8772442 0.92 MAPK1 (0.67) CES2CES1TSHRALOX15CA1
Chloroform SCHEMBL28064326 0.92 CES2 (0.56) CES2CES1TSHRALOX15CA1
Acetone SCHEMBL28066930 0.92 CES2 (0.56) CES2CES1TSHRALOX15CA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 8118 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117902997-B Amine antioxidant and preparation method and application thereof PETROCHINA COMPANY LIMITED (CN) 2026-05-26 CN claimed
CN-122071407-A Preparation method and application of 4,4' -dichlorobenzophenone 广州天赐高新材料股份有限公司 2026-05-22 CN claimed
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
US-12624165-B2 Polyether ketone ketone and a process for preparation thereof GHARDA CHEMICALS LIMITED (IN) 2026-05-12 US claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
CN-120142503-A Method for detecting related substances of 4-chlorobenzoyl chloride 河北广祥制药有限公司 2025-06-13 CN claimed
CN-116496445-B Star polymer, preparation method and application thereof, dispersing agent and dispersing method 中国科学院宁波材料技术与工程研究所 2025-05-30 CN claimed
CN-119977778-A Preparation method of carboxyamidotriazole intermediate 广东银珠医药科技有限公司 2025-05-13 CN claimed
CN-119431168-B Photosensitizer and preparation method and application thereof 广州理文科技有限公司 2025-04-11 CN claimed
WO-2025068995-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS AARTI INDUSTRIES LIMITED (IN) 2025-04-03 WO claimed
EP-0111863-A1 Process for the production of beta,4-dichloro-propiophenone BAYER AG (DE) 1984-06-27 EP claimed
EP-0057844-B1 PROCESS FOR THE PREPARATION OF POLYCHLOROBENZOYL CHLORIDES BAYER AG (DE) 1983-12-28 EP claimed
EP-0057844-A1 Process for the preparation of polychlorobenzoyl chlorides BAYER AG (DE) 1982-08-18 EP claimed
US-4142853-A BENZOYLATION SHIKIBO LIMITED (JP) 1979-03-06 US claimed
US-4123447-A REACTING (1,5-CYCLOOCTADIENE)BIS(TRIETHYLPHOSPHINE)-NICKEL(O) WITH AN ACYL HALIDE, OLIGOMERIZATION CATALYSTS PHILLIPS PETROLEUM COMPANY (US) 1978-10-31 US claimed
US-4113774-A ACETALDEHYDE DEHYDROGENASE INHIBITORS, TREATMENT OF ALCOHOLISM STERLING DRUG INC. (US) 1978-09-12 US claimed
US-4113431-A CELLULOSE REACTED WITH A BENZOYLATING AGENT SHIKIBO LIMITED (JP) 1978-09-12 US claimed
US-4104278-A Process for the production of compounds with antiphlogistic activity TROPONWERKE DINKLAGE & CO. (DE) 1978-08-01 US claimed
US-4093638-A Simultaneous preparation of organic acid chlorides and trichloroacryloyl chloride and product PRODUITS CHIMIQUES PECHINEY-SAINT-GOBAIN (FR) 1978-06-06 US claimed
US-3998844-A WITH AN AROYL CHLORIDE TO FORM A 5-AROYL-1-ALKYLPYRROLE-2-ACETIC ACID DERIVATIVE MCNEIL LABORATORIES, INCORPORATED (US) 1976-12-27 US claimed