Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.56 |
| ▸ | CES1 | P23141 | 3/20 | 0.56 |
| ▸ | TSHR | P16473 | 2/20 | 0.54 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.54 |
| ▸ | CA1 | P00915 | 2/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | GSK3B | P49841 | 2/20 | 0.48 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1854 | 0.92 | CES2 (0.65) | CES2CES1TSHRALOX15CA1 | |
| SCHEMBL5757987 | 0.92 | CES2 (0.65) | CES2CES1TSHRALOX15CA1 | |
| SCHEMBL1330271 | 0.92 | CES2 (0.65) | CES2CES1TSHRALOX15CA1 | |
| Bromide SCHEMBL28583978 | 0.90 | CES2 (0.62) | CES2CES1TSHRALOX15CA1 | |
| Ammonia Solution, Strong SCHEMBL28864885 | 0.90 | CES2 (0.62) | CES2CES1TSHRALOX15CA1 | |
| Hydrochloric Acid SCHEMBL5565187 | 0.90 | CES2 (0.62) | CES2CES1TSHRALOX15CA1 | |
| Dimethylamine SCHEMBL27770145 | 0.88 | CES2 (0.54) | CES2CES1TSHRALOX15CA1 | |
| SCHEMBL7349867 | 0.87 | CES2 (0.59) | CES2CES1TSHRALOX15CA1 | |
| Alcohol SCHEMBL27902919 | 0.86 | CES2 (0.52) | CES2CES1TSHRALOX15CA1 | |
| SCHEMBL2902010 | 0.85 | CES2 (0.56) | CES2CES1TSHRALOX15CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103113294-B | The synthetic method of rebamipide | ZHEJIANG YUANLIJIAN PHARMACEUTICAL CO., LTD. (CN) | 2016-04-27 | — | — | CN | disclosed |