SCHEMBL18540202

SCHEMBL18540202

C=CCCc1ccc(CCCCc2ccc(-c3ccc(CCC=C)c(F)c3F)cc2F)cc1

nearest known ligand 0.32

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC8 Q9BY41 1/20 0.32
RARA P10276 1/20 0.32
RARG P13631 1/20 0.32
FFAR4 Q5NUL3 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17487517 0.88 RARB (0.34) RARB
SCHEMBL18540201 0.87 RARB (0.32) RARB
SCHEMBL18540229 0.84 TAAR1 (0.36) RARBRARARARG
SCHEMBL18540030 0.84 CHKA (0.36)
SCHEMBL18540197 0.83 RARB (0.41) RARBHDAC1HDAC8RARARARG
SCHEMBL18540258 0.83 RARB (0.36) RARBHDAC1HDAC8RARARARG
SCHEMBL18540125 0.81 RARB (0.32) RARB
SCHEMBL18540037 0.81 CHKA (0.36)
SCHEMBL18540032 0.81 HDAC1 (0.36) HDAC1HDAC8
SCHEMBL17487595 0.81 CHKA (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed