SCHEMBL18540258

SCHEMBL18540258

C=CCCc1ccc(-c2ccc(CCCCc3ccc(CCC=C)c(F)c3)cc2)cc1

nearest known ligand 0.36

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
RARB P10826 3/20 0.36
RARA P10276 1/20 0.36
RARG P13631 1/20 0.36
MAOB P27338 1/20 0.34
HDAC1 Q13547 1/20 0.34
HDAC8 Q9BY41 1/20 0.34
TAAR1 Q96RJ0 1/20 0.33
S1PR1 P21453 1/20 0.33
BCHE P06276 1/20 0.31
HTR2A P28223 1/20 0.31
HTR2C P28335 1/20 0.31
THRB P10828 1/20 0.31
ESR1 P03372 1/20 0.31
CYP19A1 P11511 1/20 0.31
ESR2 Q92731 1/20 0.31
IGF1R P08069 2/20 0.30
ALOX15 P16050 2/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18540032 0.95 HDAC1 (0.36) HDAC1HDAC8S1PR1BCHEHTR2A
SCHEMBL18540041 0.94 HDAC1 (0.37) HDAC1HDAC8S1PR1BCHEHTR2A
SCHEMBL18540197 0.92 RARB (0.41) RARBRARARARGHDAC1HDAC8
SCHEMBL18540216 0.90 HTR2A (0.36) RARBRARARARGMAOBTAAR1
SCHEMBL18540068 0.89 HTR2A (0.38) TAAR1HTR2AHTR2C
SCHEMBL18540220 0.85 RARB (0.35) RARBHTR2AHTR2C
SCHEMBL18540264 0.85 MAOB (0.33) MAOBTAAR1HTR2AHTR2C
SCHEMBL18540031 0.84 HTR2A (0.38) RARBRARARARGMAOBTAAR1
SCHEMBL18540229 0.84 TAAR1 (0.36) RARBRARARARGMAOBTAAR1
SCHEMBL18540268 0.83 RARB (0.46) RARBRARARARGMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed