SCHEMBL18540229

SCHEMBL18540229

C=CCCc1ccc(-c2ccc(CCc3ccc(CCC=C)c(F)c3F)c(F)c2)cc1

nearest known ligand 0.36

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 1/20 0.36
MAOB P27338 2/20 0.33
HTR2A P28223 1/20 0.33
HTR2C P28335 1/20 0.33
RARB P10826 2/20 0.33
RARA P10276 1/20 0.33
RARG P13631 1/20 0.33
CYP17A1 P05093 2/20 0.33
CYP11B1 P15538 2/20 0.33
CYP11B2 P19099 2/20 0.33
KIF11 P52732 1/20 0.32
CYP3A4 P08684 1/20 0.31
CYP19A1 P11511 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18540031 0.92 HTR2A (0.38) TAAR1MAOBHTR2AHTR2CRARB
SCHEMBL18540216 0.91 HTR2A (0.36) TAAR1MAOBHTR2AHTR2CRARB
SCHEMBL18540147 0.90 RARB (0.44) RARBRARARARG
SCHEMBL18540202 0.84 RARB (0.32) RARBRARARARG
SCHEMBL18540258 0.84 RARB (0.36) TAAR1MAOBHTR2AHTR2CRARB
SCHEMBL2479271 0.84 RARB (0.36) TAAR1MAOBRARBRARARARG
SCHEMBL18540192 0.83 TAAR1 (0.33) TAAR1MAOBRARBRARARARG
SCHEMBL18540239 0.83 MAOB (0.43) MAOB
SCHEMBL18540264 0.81 MAOB (0.33) TAAR1MAOBHTR2AHTR2C
SCHEMBL8578398 0.81 MAOB (0.39) TAAR1MAOBRARBRARARARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed