SCHEMBL18540237

SCHEMBL18540237

C=CCCc1ccc(COc2ccc(-c3ccc(CCC=C)c(F)c3)cc2F)c(F)c1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NAAA Q02083 6/20 0.36
RXRG P48443 2/20 0.34
ERN1 O75460 1/20 0.34
FFAR1 O14842 1/20 0.34
MEN1 O00255 1/20 0.33
ALDH1A1 P00352 1/20 0.33
POLB P06746 1/20 0.33
HPGD P15428 1/20 0.33
KMT2A Q03164 1/20 0.33
CYP17A1 P05093 1/20 0.33
PPARD Q03181 2/20 0.32
PPARA Q07869 2/20 0.32
RXRA P19793 1/20 0.32
RXRB P28702 1/20 0.32
CTSK P43235 1/20 0.32
HDAC1 Q13547 1/20 0.32
HDAC6 Q9UBN7 1/20 0.32
HDAC5 Q9UQL6 1/20 0.32
CNR2 P34972 1/20 0.32
NPC1 O15118 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18540225 0.89 MAOB (0.40) FFAR1PPARAHDAC1HDAC6HDAC5
SCHEMBL18540157 0.88 NAAA (0.34) NAAARXRGERN1FFAR1MEN1
SCHEMBL18540243 0.83 MAOB (0.45) FFAR1HDAC1HDAC6HDAC5NPC1
SCHEMBL18540216 0.81 HTR2A (0.36) CYP17A1MAOB
SCHEMBL20803603 0.81 GABRA1 (0.39) NAAARXRGFFAR1CYP17A1PPARD
SCHEMBL18540224 0.81 MAOB (0.41) FFAR1PPARDHDAC1HDAC6HDAC5
SCHEMBL20803619 0.81 NAAA (0.45) NAAARXRGFFAR1MEN1ALDH1A1
SCHEMBL20803602 0.81 NAAA (0.41) NAAARXRGFFAR1CYP17A1PPARD
SCHEMBL20803652 0.80 GABRA1 (0.40) NAAARXRGFFAR1MEN1ALDH1A1
SCHEMBL18540062 0.80 S1PR5 (0.39) ERN1FFAR1MAOBS1PR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed