SCHEMBL18540264

SCHEMBL18540264

C=CCCc1ccc(-c2ccc(C/C=C/Cc3ccc(CCC=C)c(F)c3)cc2)cc1

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.33
ALOX5 P09917 2/20 0.32
GABRA1 P14867 2/20 0.32
CNR2 P34972 2/20 0.32
GABRB2 P47870 2/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
GAA P10253 1/20 0.32
MAPT P10636 1/20 0.32
GABRB1 P18505 1/20 0.32
RXRA P19793 1/20 0.32
CNR1 P21554 1/20 0.32
GABRA5 P31644 1/20 0.32
GABRA3 P34903 1/20 0.32
GABRA2 P47869 1/20 0.32
KMT2A Q03164 1/20 0.32
ACE2 Q9BYF1 1/20 0.32
SIRT3 Q9NTG7 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
HTR2A P28223 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18540192 0.93 TAAR1 (0.33) MAOBALOX5GABRA1CNR2GABRB2
SCHEMBL18540196 0.89 CNR2 (0.32) ALOX5GABRA1CNR2GABRB2MEN1
SCHEMBL18540047 0.87 MAOB (0.31) MAOB
SCHEMBL18540258 0.85 RARB (0.36) MAOBTAAR1HTR2AHTR2C
SCHEMBL18540216 0.84 HTR2A (0.36) MAOBTAAR1HTR2AHTR2C
SCHEMBL18540088 0.84 ALOX5 (0.33) MAOBALOX5GABRA1CNR2GABRB2
SCHEMBL18540068 0.83 HTR2A (0.38) TAAR1HTR2AHTR2C
SCHEMBL18540033 0.83 HDAC1 (0.33)
SCHEMBL18540031 0.82 HTR2A (0.38) MAOBGABRA1GABRB2TAAR1HTR2A
SCHEMBL18540248 0.82 RARB (0.31) ALOX5TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed
US-20170051206-A1 LIQUID CRYSTAL COMPOUND HAVING ALKENYL ON BOTH ENDS, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC CORPORATION (JP) 2017-02-23 US disclosed