Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.36 |
| ▸ | HTR3B | O95264 | 1/20 | 0.36 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17224304 | 0.90 | PTGS2 (0.51) | PTGS2MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL17224302 | 0.90 | PTGS2 (0.51) | PTGS2MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL17224339 | 0.84 | MEN1 (0.50) | PTGS2MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL17224340 | 0.84 | MEN1 (0.50) | PTGS2MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL17224277 | 0.76 | TUBB1 (0.53) | PTGS2MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL17224276 | 0.76 | TUBB1 (0.53) | PTGS2MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL17224393 | 0.76 | TUBB1 (0.46) | PTGS2MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL17224395 | 0.76 | TUBB1 (0.46) | PTGS2MEN1GAAKMT2AL3MBTL1 | |
| SCHEMBL17224345 | 0.73 | PTGS1 (0.59) | MEN1GAAKMT2AL3MBTL1NPC1 | |
| SCHEMBL17224400 | 0.73 | PTGS1 (0.59) | MEN1GAAKMT2AL3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170051149-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-02-23 | — | — | US | disclosed |