Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | NPY4R | P50391 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | FPR2 | P25090 | 4/20 | 0.38 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.37 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12119403 | 0.89 | TGM2 (0.61) | TGM2NPY4RKMT2AUSP2RXFP1 | |
| Hydrochloric Acid SCHEMBL13737398 | 0.88 | TGM2 (0.60) | TGM2NPY4RKMT2AUSP2RXFP1 | |
| SCHEMBL12763951 | 0.84 | POLB (0.50) | TGM2KMT2AUSP2RXFP1MEN1 | |
| SCHEMBL12763953 | 0.83 | MEN1 (0.44) | TGM2KMT2AUSP2RXFP1MEN1 | |
| SCHEMBL22636637 | 0.81 | TGM2 (0.43) | TGM2KMT2AUSP2RXFP1MEN1 | |
| SCHEMBL18087519 | 0.80 | TGM2 (0.62) | TGM2NPY4RKMT2AUSP2RXFP1 | |
| SCHEMBL17399553 | 0.78 | TGM2 (0.65) | TGM2NPY4RKMT2AUSP2RXFP1 | |
| SCHEMBL12763952 | 0.78 | MEN1 (0.44) | TGM2NPY4RKMT2AUSP2RXFP1 | |
| SCHEMBL9290111 | 0.78 | ABCB1 (0.46) | TGM2KMT2AUSP2RXFP1MEN1 | |
| SCHEMBL12870952 | 0.77 | TGM2 (0.60) | TGM2NPY4RKMT2AUSP2RXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170051149-A1 | AZOARYLS AS REVERSIBLY MODULATABLE TUBULIN INHIBITORS | ECOLE NORMALE SUPERIEURE DE LYON (FR) | 2017-02-23 | — | — | US | disclosed |