Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | BLM | P54132 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | USP2 | O75604 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | PPARG | P37231 | 1/20 | 0.53 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.53 |
| ▸ | FPR2 | P25090 | 4/20 | 0.48 |
| ▸ | NPY4R | P50391 | 3/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | AVPR2 | P30518 | 4/20 | 0.46 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.42 |
| ▸ | APLNR | P35414 | 2/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL13737398 | 0.99 | TGM2 (0.60) | TGM2MEN1BLMKMT2AUSP2 | |
| SCHEMBL18087519 | 0.92 | TGM2 (0.62) | TGM2MEN1BLMKMT2AUSP2 | |
| SCHEMBL17399553 | 0.90 | TGM2 (0.65) | TGM2MEN1BLMKMT2AUSP2 | |
| SCHEMBL18540754 | 0.89 | TGM2 (0.48) | TGM2MEN1BLMKMT2AUSP2 | |
| SCHEMBL12870952 | 0.88 | TGM2 (0.60) | TGM2MEN1BLMKMT2AUSP2 | |
| Piperazine SCHEMBL1317991 | 0.88 | MEN1 (0.55) | TGM2MEN1BLMKMT2AUSP2 | |
| SCHEMBL18732968 | 0.88 | TGM2 (0.61) | TGM2MEN1BLMKMT2AUSP2 | |
| SCHEMBL18067135 | 0.88 | TGM2 (0.60) | TGM2MEN1BLMKMT2AUSP2 | |
| SCHEMBL13103120 | 0.88 | TGM2 (0.61) | TGM2MEN1BLMKMT2AUSP2 | |
| SCHEMBL13114580 | 0.86 | TGM2 (0.59) | TGM2MEN1BLMKMT2AUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3391056-B1 | CHROMOGENIC PEROXIDASE SUBSTRATES | AGILENT TECHNOLOGIES INC (US) | 2024-01-17 | — | — | EP | disclosed |
| US-10017527-B2 | KLK4 inhibitors | UNIVERSITEIT ANTWERPEN (BE) | 2018-07-10 | — | — | US | disclosed |
| US-20170175178-A1 | CHROMOGENIC PEROXIDASE SUBSTRATES | DAKO DENMARK APS (DK) | 2017-06-22 | — | — | US | disclosed |
| US-20170101427-A1 | NOVEL KLK4 INHIBITORS | UNIVERSITEIT ANTWERPEN (BE) | 2017-04-13 | — | — | US | disclosed |
| WO-2015124690-A1 | COMPOSITION COMPRISING A FRET PAIR WITH A DEFINED GEOMETRY | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2015-08-27 | — | — | WO | disclosed |
| US-8771642-B2 | Active particles for bio-analytical applications and methods for their preparation | Alma Mater Studiorum—Universita' di Bologna (IT) | 2014-07-08 | — | — | US | disclosed |
| US-20140079632-A1 | ACTIVITY-BASED PROBES FOR THE UROKINASE PLASMINOGEN ACTIVATOR | UNIVERSITEIT ANTWERPEN (BE) | 2014-03-20 | — | — | US | disclosed |
| WO-2012152807-A1 | ACTIVITY-BASED PROBES FOR THE UROKINASE PLASMINOGEN ACTIVATOR | UNIVERSITEIT ANTWERPEN (BE) | 2012-11-15 | — | — | WO | disclosed |
| US-20110274621-A1 | Active Particles for Bio-Analytical Applications and Methods for Their Preparation | ALMA MATER STUDIORUM-UNIVERSITA'DI BOLOGNA (IT) | 2011-11-10 | — | — | US | disclosed |
| US-20110274621-A1 | Active Particles for Bio-Analytical Applications and Methods for Their Preparation | ALMA MATER STUDIORUM-UNIVERSITA'DI BOLOGNA (IT) | 2011-11-10 | — | — | US | disclosed |
| US-7820833-B2 | Dithio compounds | MARQUETTE UNIVERSITY (US) | 2010-10-26 | — | — | US | disclosed |
| US-7820833-B2 | Dithio compounds | MARQUETTE UNIVERSITY (US) | 2010-10-26 | — | — | US | disclosed |
| WO-2010013136-A2 | ACTIVE PARTICLES FOR BIO-ANALYTICAL APPLICATIONS AND METHODS FOR THEIR PREPARATION | ALMA MATER STUDIORUM - UNIVERSITA' DI BOLOGNA (IT) | 2010-02-04 | — | — | WO | disclosed |
| US-20070054410-A1 | include at least one fluorophore; may be used as reagents for detecting thiol-containing compounds; fluorescein isothiocyantate/rhodamine B diamino phenyl disulfide compound | MARQUETTE UNIVERSITY | 2007-03-08 | — | — | US | disclosed |
| US-20070054410-A1 | include at least one fluorophore; may be used as reagents for detecting thiol-containing compounds; fluorescein isothiocyantate/rhodamine B diamino phenyl disulfide compound | MARQUETTE UNIVERSITY | 2007-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170175178-A1 | CHROMOGENIC PEROXIDASE SUBSTRATES | MPO, TPO, TYR | TGM2 407/4885MEN1 3360/4885BLM 1525/4885 |
| US-10017527-B2 | KLK4 inhibitors | KLK4, KLK3, KLK1 | TGM2 944/4885MEN1 3183/4885BLM 4546/4885 |
| US-20070054410-A1 | include at least one fluorophore; may be used as reagents for detecting thiol-containing compounds; fluorescein isothiocyantate/rhodamine B diamino phenyl disulfide compound | TST, PFAS, SQOR | TGM2 749/4885MEN1 4714/4885BLM 3007/4885 |
| US-20110274621-A1 | Active Particles for Bio-Analytical Applications and Methods for Their Preparation | PHOSPHO1, LIPA, ALG1 | TGM2 1240/4885MEN1 294/4885BLM 2780/4885 |
| US-20140079632-A1 | ACTIVITY-BASED PROBES FOR THE UROKINASE PLASMINOGEN ACTIVATOR | PLAU, SERPINE1, PRSS3 | TGM2 343/4885MEN1 2509/4885BLM 2464/4885 |
| US-20170101427-A1 | NOVEL KLK4 INHIBITORS | KLK4, KLK3, KLK1 | TGM2 718/4885MEN1 3716/4885BLM 4497/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.