Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 13/20 | 0.67 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21064802 | 0.94 | DGAT1 (0.71) | DGAT1SCN9A | |
| SCHEMBL20428727 | 0.91 | DGAT1 (0.70) | DGAT1EPHX2SCN9AKCNH2SCN5A | |
| SCHEMBL18541127 | 0.91 | DGAT1 (0.81) | DGAT1 | |
| SCHEMBL16661343 | 0.90 | DGAT1 (0.83) | DGAT1EPHX2SCN9AKCNH2SCN5A | |
| SCHEMBL21064878 | 0.87 | DGAT1 (0.67) | DGAT1SCN9A | |
| SCHEMBL18541129 | 0.85 | DGAT1 (0.67) | DGAT1 | |
| SCHEMBL16661347 | 0.85 | DGAT1 (0.58) | DGAT1KCNH2 | |
| SCHEMBL18541121 | 0.84 | DGAT1 (0.82) | DGAT1 | |
| SCHEMBL18541128 | 0.84 | DGAT1 (0.82) | DGAT1 | |
| SCHEMBL18541122 | 0.83 | DGAT1 (0.82) | DGAT1SCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170050950-A1 | AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-02-23 | — | — | US | disclosed |
| US-20170050950-A1 | AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170050950-A1 | AROMATIC HETEROCYCLIC COMPOUND | GPR119, NR0B1, BET1 | DGAT1 1688/4885EPHX2 2709/4885SCN9A 1345/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.