Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD5 | P21918 | 1/20 | 0.47 |
| ▸ | SCNN1A | P37088 | 1/20 | 0.47 |
| ▸ | SCNN1B | P51168 | 1/20 | 0.47 |
| ▸ | SCNN1G | P51170 | 1/20 | 0.47 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.47 |
| ▸ | ATR | Q13535 | 3/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 3/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | BDKRB1 | P46663 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | HRH2 | P25021 | 2/20 | 0.32 |
| ▸ | HRH1 | P35367 | 2/20 | 0.32 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.31 |
| ▸ | KLK1 | P06870 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18541299 | 0.92 | DRD5 (0.48) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538912 | 0.92 | DRD5 (0.48) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541361 | 0.90 | DRD5 (0.47) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538929 | 0.90 | DRD5 (0.57) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541232 | 0.87 | DRD5 (0.56) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541300 | 0.82 | DRD5 (0.58) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541251 | 0.81 | DRD5 (0.58) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18538925 | 0.81 | DRD5 (0.57) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541359 | 0.80 | DRD5 (0.53) | DRD5SCNN1ASCNN1BSCNN1GHRH3 | |
| SCHEMBL18541250 | 0.79 | DRD5 (0.55) | DRD5SCNN1ASCNN1BSCNN1GHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017028926-A1 | NOVEL ANNELATED BENZAMIDES | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-02-23 | — | — | WO | disclosed |