Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18543718 | 0.88 | HTT (0.44) | HTTTSHRMEN1KMT2AUSP2 | |
| SCHEMBL263789 | 0.76 | HTT (0.43) | POLBHTTTSHRMEN1KMT2A | |
| SCHEMBL28430986 | 0.75 | POLB (0.53) | POLBHTTTSHRKDM4EMEN1 | |
| SCHEMBL5552878 | 0.74 | POLB (0.50) | POLBHTTTSHRKDM4EMEN1 | |
| SCHEMBL7181697 | 0.72 | HTT (0.45) | POLBHTTTSHRMEN1KMT2A | |
| SCHEMBL9545140 | 0.72 | POLB (0.51) | POLBTSHRKDM4EMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL9241189 | 0.71 | POLB (0.50) | POLBTSHRKDM4EMEN1KMT2A | |
| SCHEMBL28431266 | 0.71 | SMN1; SMN2 (0.47) | POLBHTTTSHRKDM4EMEN1 | |
| SCHEMBL13685280 | 0.70 | CYP1A2 (0.48) | POLBTSHRKDM4EMEN1KMT2A | |
| SCHEMBL262699 | 0.70 | CYP2C9 (0.47) | TSHRMEN1KMT2AUSP2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443482-B1 | BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | claimed |