Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18543716 | 0.88 | POLB (0.42) | HTTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL262699 | 0.82 | CYP2C9 (0.47) | KMT2AMEN1USP2L3MBTL1TSHR | |
| SCHEMBL263789 | 0.75 | HTT (0.43) | HTTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL7181697 | 0.73 | HTT (0.45) | HTTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL7190904 | 0.72 | HTT (0.46) | HTTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL8205275 | 0.72 | HTT (0.46) | HTTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL2885668 | 0.72 | HTT (0.45) | HTTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL28256758 | 0.72 | HTT (0.45) | HTTKMT2AMEN1USP2L3MBTL1 | |
| Potassium Ion SCHEMBL4430077 | 0.71 | HTT (0.54) | HTTKMT2AMEN1USP2L3MBTL1 | |
| SCHEMBL2230565 | 0.71 | HTT (0.54) | HTTKMT2AMEN1USP2L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2443482-B1 | BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. | BAUSCH & LOMB (US) | 2017-03-01 | — | — | EP | claimed |