SCHEMBL263789

SCHEMBL263789

CCc1cccc2c1C(C(CC)C(=O)Oc1ccccc1)c1ccccc1O2

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HTT P42858 1/20 0.43
L3MBTL1 Q9Y468 4/20 0.39
KMT2A Q03164 4/20 0.38
CYP1A2 P05177 3/20 0.38
CHRM2 P08172 2/20 0.38
CYP2D6 P10635 2/20 0.38
CHRM1 P11229 2/20 0.38
KCNH2 Q12809 2/20 0.38
LMNA P02545 2/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TSHR P16473 2/20 0.38
CYP3A4 P08684 1/20 0.38
NFKB1 P19838 1/20 0.38
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 1/20 0.37
APEX1 P27695 1/20 0.37
RECQL P46063 1/20 0.37
PMP22 Q01453 1/20 0.37
TDP1 Q9NUW8 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18543716 0.76 POLB (0.42) HTTL3MBTL1KMT2ATSHRMAPT
SCHEMBL18543718 0.75 HTT (0.44) HTTL3MBTL1KMT2ALMNACYP2C9
SCHEMBL11793574 0.72 L3MBTL1 (0.51) HTTL3MBTL1KMT2ACYP1A2LMNA
SCHEMBL7181697 0.72 HTT (0.45) HTTL3MBTL1KMT2ACYP1A2CHRM2
SCHEMBL2451297 0.71 L3MBTL1 (0.43) HTTL3MBTL1KMT2ACYP1A2CHRM2
SCHEMBL7190904 0.68 HTT (0.46) HTTL3MBTL1KMT2ACYP1A2CHRM2
SCHEMBL8205275 0.68 HTT (0.46) HTTL3MBTL1KMT2ALMNATSHR
SCHEMBL2885668 0.68 HTT (0.45) HTTL3MBTL1KMT2ALMNACYP2C9
SCHEMBL28256758 0.68 HTT (0.45) HTTL3MBTL1KMT2ALMNATSHR
SCHEMBL2230565 0.67 HTT (0.54) HTTL3MBTL1KMT2ACYP1A2CHRM2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2443482-B1 BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. BAUSCH & LOMB (US) 2017-03-01 EP claimed
EP-2443482-A2 BIOMEDICAL DEVICES Bausch & Lomb Incorporated (US) 2012-04-25 EP claimed
WO-2010147864-A2 BIOMEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2010-12-23 WO claimed
US-20100315588-A1 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2010-12-16 US claimed
US-20240240047-A1 BIOMEDICAL DEVICES HAVING A SURFACE COATING JPMORGAN CHASE BANK, N.A., AS SUCCESSOR AGENT 2024-07-18 US disclosed
US-10668676-B2 Ophthalmic devices BAUSCH & LOMB INCORPORATED (US) 2020-06-02 US disclosed
US-20200047437-A1 OPHTHALMIC DEVICES MEDICIS PHARMACEUTICAL CORPORATION 2020-02-13 US disclosed
EP-2443485-B1 BIOMEDICAL DEVICES BAUSCH & LOMB (US) 2017-11-08 EP disclosed
EP-2443486-B1 BIOMEDICAL DEVICES BAUSCH & LOMB (US) 2017-03-01 EP disclosed
EP-2443482-B1 BIOMEDICAL DEVICES, POLYMERIC MATERIALS AND CONTACT LENSES COMPRISING THE SAME. BAUSCH & LOMB (US) 2017-03-01 EP disclosed
EP-2443482-A2 BIOMEDICAL DEVICES Bausch & Lomb Incorporated (US) 2012-04-25 EP disclosed
EP-2443486-A2 BIOMEDICAL DEVICES Bausch & Lomb Incorporated (US) 2012-04-25 EP disclosed
US-8133960-B2 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2012-03-13 US disclosed
US-8083348-B2 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2011-12-27 US disclosed
WO-2010147875-A2 BIOMEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2010-12-23 WO disclosed
WO-2010147864-A2 BIOMEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2010-12-23 WO disclosed
WO-2010147876-A2 BIOMEDICAL DEVICES BAUSCH & LOMB INCORPORATED (US) 2010-12-23 WO disclosed
US-20100317816-A1 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2010-12-16 US disclosed
US-20100317817-A1 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2010-12-16 US disclosed
US-20100315588-A1 Biomedical devices BAUSCH & LOMB INCORPORATED (US) 2010-12-16 US disclosed