SCHEMBL18543992

SCHEMBL18543992

CCC(CC(CC)=Nc1c(C(C)C)cccc1C(C)C)=Nc1c(C(C)C)cccc1C(C)C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 3/20 0.42
GABRG2 P18507 2/20 0.42
GABRB3 P28472 2/20 0.42
LMNA P02545 2/20 0.42
GABRB2 P47870 2/20 0.42
TSHR P16473 2/20 0.42
FAAH O00519 1/20 0.42
CA1 P00915 1/20 0.42
CA2 P00918 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
HPGD P15428 1/20 0.42
GABRB1 P18505 1/20 0.42
PTGS1 P23219 1/20 0.42
SLC6A2 P23975 1/20 0.42
HTR2C P28335 1/20 0.42
GABRA5 P31644 1/20 0.42
GABRA3 P34903 1/20 0.42
HTR2B P41595 1/20 0.42
GABRA2 P47869 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18543990 1.00 GABRA1 (0.42) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL21192631 0.89 LMNA (0.40) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL21192630 0.89 LMNA (0.40) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL21192699 0.85 LMNA (0.37) GABRA1GABRG2GABRB3LMNAKMT2A
SCHEMBL21192701 0.85 LMNA (0.37) GABRA1GABRG2GABRB3LMNAKMT2A
SCHEMBL13613946 0.83 GABRA1 (0.44) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL28857733 0.82 SOAT1 (0.40) SOAT1
SCHEMBL18544027 0.81 GABRA1 (0.45) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL4059495 0.81 GABRA1 (0.45) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL18544029 0.81 GABRA1 (0.45) GABRA1GABRG2GABRB3LMNAGABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3135697-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2019-08-14 EP claimed
US-10208145-B2 Catalyst component for olefin polymerization, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-02-19 US claimed
CN-105085731-B A kind of catalyst component for olefin polymerization preparation method and corresponding catalyst 中国石油化工股份有限公司 2017-09-29 CN claimed
US-20170073441-A1 Catalyst Component For Olefin Polymerization, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-03-16 US claimed
EP-3135697-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2017-03-01 EP claimed
EP-3135697-B1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2019-08-14 EP disclosed
US-10208145-B2 Catalyst component for olefin polymerization, and catalyst containing the same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2019-02-19 US disclosed
CN-105085733-B A kind of catalyst component for olefin polymerization preparation method and corresponding catalyst 中国石油化工股份有限公司 2017-10-03 CN disclosed
CN-105085727-B A kind of catalytic component and its catalyst for olefinic polymerization 中国石油化工股份有限公司 2017-09-29 CN disclosed
CN-105085731-B A kind of catalyst component for olefin polymerization preparation method and corresponding catalyst 中国石油化工股份有限公司 2017-09-29 CN disclosed
US-20170073441-A1 Catalyst Component For Olefin Polymerization, and Catalyst Containing the Same CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2017-03-16 US disclosed
EP-3135697-A1 CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND CATALYST THEREOF China Petroleum & Chemical Corporation (CN) 2017-03-01 EP disclosed