Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 5/20 | 0.37 |
| ▸ | CSF1R | P07333 | 2/20 | 0.35 |
| ▸ | LOX | P28300 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22996915 | 0.87 | KCNH2 (0.37) | KCNH2CSF1RPDGFRBPDGFRA | |
| SCHEMBL2821504 | 0.85 | KCNH2 (0.37) | KCNH2CSF1RPDGFRBPDGFRA | |
| SCHEMBL2931872 | 0.82 | CSF1R (0.40) | KCNH2CSF1R | |
| SCHEMBL1712323 | 0.82 | CCNB2 (0.36) | KCNH2CSF1R | |
| SCHEMBL2932060 | 0.81 | PTGS2 (0.39) | KCNH2 | |
| SCHEMBL4214402 | 0.79 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL4214405 | 0.79 | KCNH2 (0.36) | KCNH2 | |
| SCHEMBL2822572 | 0.79 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL18544262 | 0.78 | PDGFRB (0.36) | KCNH2CSF1RMAP4K4PDGFRBPDGFRA | |
| SCHEMBL2821252 | 0.78 | PDGFRB (0.36) | CSF1RMAP4K4PDGFRBPDGFRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017029602-A2 | COMPOUNDS FOR USE IN ANTIBACTERIAL APPLICATIONS | GLAXOSMITHKLINE INTELLECTUAL PROPERTY DEVELOPMENT LIMITED (GB) | 2017-02-23 | — | — | WO | disclosed |