Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.74 |
| ▸ | FDPS | P14324 | 3/20 | 0.69 |
| ▸ | PTGES | O14684 | 4/20 | 0.67 |
| ▸ | APP | P05067 | 6/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | BACE1 | P56817 | 3/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.62 |
| ▸ | TOP2A | P11388 | 2/20 | 0.62 |
| ▸ | MAPT | P10636 | 2/20 | 0.62 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.62 |
| ▸ | SNCA | P37840 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.62 |
| ▸ | CA12 | O43570 | 1/20 | 0.62 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.62 |
| ▸ | PLIN1 | O60240 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18544347 | 1.00 | NFE2L2 (0.74) | NFE2L2FDPSPTGESAPPKDM4E | |
| Hydrochloric Acid SCHEMBL27175580 | 0.99 | NFE2L2 (0.72) | NFE2L2FDPSPTGESAPPKDM4E | |
| SCHEMBL18570139 | 0.99 | NFE2L2 (0.76) | NFE2L2FDPSPTGESAPPKDM4E | |
| Hydrochloric Acid SCHEMBL30884509 | 0.97 | NFE2L2 (0.70) | NFE2L2FDPSPTGESAPPKDM4E | |
| Hydrochloric Acid SCHEMBL18544374 | 0.97 | NFE2L2 (0.70) | NFE2L2FDPSPTGESAPPKDM4E | |
| Hydrochloric Acid SCHEMBL18544375 | 0.97 | NFE2L2 (0.70) | NFE2L2FDPSPTGESAPPKDM4E | |
| SCHEMBL23765362 | 0.96 | NFE2L2 (0.72) | NFE2L2FDPSPTGESAPPKDM4E | |
| SCHEMBL18569871 | 0.95 | NFE2L2 (0.67) | NFE2L2FDPSPTGESAPPKDM4E | |
| SCHEMBL20906942 | 0.92 | FDPS (0.67) | NFE2L2FDPSPTGESAPPKDM4E | |
| SCHEMBL21155668 | 0.92 | NFE2L2 (0.62) | NFE2L2FDPSPTGESAPPKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3135110-A1 | 1,7-DIARYL-1,6-HEPTADIEN-3,5-DION DERIVATIVES, METHODS OF MAKING AND USING THE SAME | Universitätsklinikum Regensburg (DE) | 2017-03-01 | — | — | EP | disclosed |