Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | PPID | Q08752 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7983508 | 0.91 | DPP7 (0.40) | OPRL1SMN1; SMN2KMT2ADPP7 | |
| SCHEMBL2545928 | 0.80 | METAP2 (0.42) | OPRM1METAP2LMNAATMKMT2A | |
| SCHEMBL2545929 | 0.80 | METAP2 (0.42) | OPRM1METAP2LMNAATMKMT2A | |
| SCHEMBL10002339 | 0.76 | CXCR4 (0.36) | RAB9AHDAC8HDAC6 | |
| SCHEMBL337364 | 0.74 | LMNA (0.45) | SMN1; SMN2LMNA | |
| SCHEMBL20240379 | 0.74 | OPRL1 (0.43) | OPRL1OPRM1KMT2A | |
| SCHEMBL336767 | 0.74 | LMNA (0.45) | SMN1; SMN2LMNA | |
| SCHEMBL14718566 | 0.72 | DPP4 (0.40) | OPRL1OPRM1RAB9AKMT2ADPP7 | |
| SCHEMBL25249805 | 0.71 | KMT2A (0.39) | KMT2ADPP7 | |
| SCHEMBL12492863 | 0.70 | AVPR1A (0.43) | KDM4EOPRL1OPRM1RIPK1METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3004084-B1 | SUBSTITUTED BENZOXAZOLES | Bayer Pharma AG (DE) | 2017-03-01 | — | — | EP | disclosed |