SCHEMBL18545245

SCHEMBL18545245

O=C1C2CCC3C(=O)N(CCOCCO)C(=O)C4CCC(C(=O)N1CCCOCCO)C2C34

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.36
TSHR P16473 3/20 0.36
USP2 O75604 1/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36
MGLL Q99685 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
KMT2A Q03164 2/20 0.33
L3MBTL1 Q9Y468 2/20 0.33
PABPC1 P11940 1/20 0.33
POLB P06746 2/20 0.32
TDP1 Q9NUW8 2/20 0.32
PKM P14618 1/20 0.32
CTDSP1 Q9GZU7 1/20 0.32
MEN1 O00255 1/20 0.32
ESR1 P03372 1/20 0.32
HPGD P15428 1/20 0.32
RECQL P46063 1/20 0.32
BLM P54132 1/20 0.32
MAPK1 P28482 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8549222 0.82 HTT (0.42) ALDH1A1HTTMGLLSMN1; SMN2TDP1
SCHEMBL14794932 0.82 MGLL (0.38) ALDH1A1TSHRUSP2HTTHSD17B10
SCHEMBL22012806 0.71 PPM1B (0.37) ALDH1A1TSHRUSP2HTTHSD17B10
SCHEMBL15502887 0.69 MGLL (0.59) ALDH1A1TSHRHTTMGLLSMN1; SMN2
SCHEMBL14325520 0.69 MGLL (0.42) ALDH1A1TSHRHTTMGLLSMN1; SMN2
SCHEMBL23286083 0.67 MGLL (0.41) ALDH1A1TSHRHTTMGLLSMN1; SMN2
SCHEMBL11510536 0.67 HTT (0.51) ALDH1A1TSHRUSP2HTTHSD17B10
SCHEMBL22543431 0.67 MGLL (0.45) ALDH1A1TSHRHTTMGLLSMN1; SMN2
SCHEMBL28931864 0.67 MGLL (0.45) ALDH1A1TSHRHTTMGLLSMN1; SMN2
SCHEMBL10601922 0.67 ALDH1A1 (0.47) ALDH1A1TSHRHTTMGLLKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170053721-A1 Modular Supramolecular Approach for Co-Crystallization of Donors and Acceptors into Ordered Networks UNITED STATES DEPARTMENT OF ENERGY 2017-02-23 US disclosed