Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.51 |
| ▸ | ACHE | P22303 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 4/20 | 0.35 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.32 |
| ▸ | MAOB | P27338 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | PKM | P14618 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
| ▸ | ATM | Q13315 | 2/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160777 | 0.84 | STAT3 (0.50) | STAT3ACHEESR1ESR2TRPA1 | |
| SCHEMBL6113147 | 0.84 | STAT3 (0.50) | STAT3ACHEESR1ESR2TRPA1 | |
| SCHEMBL6113339 | 0.84 | STAT3 (0.50) | STAT3ACHEESR1ESR2TRPA1 | |
| SCHEMBL16363921 | 0.82 | STAT3 (0.49) | STAT3ACHEESR1ESR2TRPA1 | |
| SCHEMBL14731702 | 0.82 | STAT3 (0.49) | STAT3ACHEESR1ESR2TRPA1 | |
| SCHEMBL14731828 | 0.82 | STAT3 (0.49) | STAT3ACHEESR1ESR2TRPA1 | |
| SCHEMBL19361091 | 0.80 | STAT3 (0.46) | STAT3ACHEESR1ESR2TRPA1 | |
| SCHEMBL6113156 | 0.76 | STAT3 (0.43) | STAT3ACHEESR1ESR2GRIA4 | |
| SCHEMBL12472097 | 0.76 | STAT3 (0.43) | STAT3ACHEESR1ESR2GRIA4 | |
| SCHEMBL6113392 | 0.76 | STAT3 (0.43) | STAT3ACHEESR1ESR2GRIA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170197977-A9 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | COGNITION THERAPEUTICS, INC. (US) | 2017-07-13 | — | — | US | disclosed |
| US-20170049723-A1 | ISOLATED COMPOUNDS FROM TURMERIC OIL AND METHODS OF USE | COGNITION THERAPEUTICS, INC. | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049723-A1 | ISOLATED COMPOUNDS FROM TURMERIC OIL AND METHODS OF USE | APP, MAPT, PSEN1 | STAT3 284/4885ACHE 6/4885ESR1 4310/4885 |
| US-20170197977-A9 | COMPOSITIONS AND METHODS FOR TREATING NEURODEGENERATIVE DISEASE | TMEM97, SLC18A2, CHRNB2 | STAT3 4589/4885ACHE 355/4885ESR1 3060/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.