Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.59 |
| ▸ | RAB9A | P51151 | 9/20 | 0.59 |
| ▸ | POLB | P06746 | 6/20 | 0.59 |
| ▸ | MYC | P01106 | 2/20 | 0.58 |
| ▸ | TCF4 | P15884 | 1/20 | 0.57 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.57 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.49 |
| ▸ | NPC1 | O15118 | 7/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TNNI3 | P19429 | 1/20 | 0.45 |
| ▸ | TNNT2 | P45379 | 1/20 | 0.45 |
| ▸ | TNNC1 | P63316 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 5/20 | 0.45 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12009070 | 1.00 | ALDH1A1 (0.59) | ALDH1A1RAB9APOLBMYCTCF4 | |
| SCHEMBL12009080 | 0.94 | MYC (0.63) | ALDH1A1RAB9APOLBMYCTCF4 | |
| SCHEMBL18545517 | 0.91 | MYC (0.67) | ALDH1A1RAB9APOLBMYCTCF4 | |
| SCHEMBL12009062 | 0.91 | MYC (0.67) | ALDH1A1RAB9APOLBMYCTCF4 | |
| SCHEMBL13446965 | 0.90 | MYC (0.61) | ALDH1A1RAB9APOLBMYCTCF4 | |
| SCHEMBL12009094 | 0.86 | MYC (0.77) | ALDH1A1RAB9APOLBMYCTCF4 | |
| SCHEMBL18545498 | 0.86 | MYC (0.77) | ALDH1A1RAB9APOLBMYCTCF4 | |
| SCHEMBL13446970 | 0.85 | MYC (0.67) | ALDH1A1RAB9APOLBMYCTCF4 | |
| SCHEMBL12009084 | 0.85 | TCF4 (0.65) | ALDH1A1RAB9APOLBMYCTCF4 | |
| SCHEMBL18545537 | 0.85 | TCF4 (0.65) | ALDH1A1RAB9APOLBMYCTCF4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170049751-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | DASGUPTA RAMANUJ (US) | 2017-02-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170049751-A1 | OXAZOLE AND THIAZOLE COMPOUNDS AS BETA-CATENIN MODULATORS AND USES THEREOF | CTNNB1, CTNNA1, CTNNBL1 | ALDH1A1 413/4885RAB9A 3367/4885POLB 2088/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.