SCHEMBL1854556

SCHEMBL1854556

CCCCCCCCc1c(O)ccc([N+](=O)[O-])c1[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.42
TYR P14679 1/20 0.42
TRPV1 Q8NER1 1/20 0.42
ESR1 P03372 1/20 0.40
TSHR P16473 2/20 0.39
GSR P00390 1/20 0.39
TXNRD1 Q16881 1/20 0.39
KAT8 Q9H7Z6 2/20 0.38
CTSB P07858 2/20 0.38
CTSH P09668 1/20 0.38
TP53 P04637 1/20 0.38
CYP3A4 P08684 1/20 0.38
HPGD P15428 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
KCNH2 Q12809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11421422 1.00 GPR35 (0.42) GPR35TYRTRPV1ESR1TSHR
SCHEMBL28899639 1.00 GPR35 (0.42) GPR35TYRTRPV1ESR1TSHR
SCHEMBL1123245 0.94 GPR35 (0.45) GPR35TRPV1TSHRCTSBCTSH
SCHEMBL5588969 0.84 TYR (0.46) TYRESR1GSRTXNRD1KAT8
SCHEMBL5587233 0.84 TYR (0.46) TYRESR1GSRTXNRD1KAT8
SCHEMBL5590461 0.84 TYR (0.46) TYRESR1GSRTXNRD1KAT8
SCHEMBL5588658 0.84 TYR (0.46) TYRESR1GSRTXNRD1KAT8
SCHEMBL5587053 0.84 TYR (0.46) TYRESR1GSRTXNRD1KAT8
SCHEMBL5691196 0.82 GPR35 (0.45) GPR35TRPV1TSHRCTSBCTSH
SCHEMBL30425872 0.82 GPR35 (0.45) GPR35TRPV1TSHRCTSBCTSH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8557866-B2 Isomeric mixtures of dinitro-octylphenyl esters and synergistic fungicidal mixtures therefrom DOW AGROSCIENCES, LLC. (US) 2013-10-15 US disclosed
EP-1830641-B1 ISOMERIC MIXTURES OF DINITRO-OCTYLPHENYL ESTERS AND SYNERGISTIC FUNGICIDAL MIXTURES THEREFROM DOW AGROSCIENCES LLC (US) 2011-05-25 EP disclosed
CN-101060780-B Isomeric mixtures of dinitro-octylphenyl esters and synergistic fungicidal mixtures therefrom DOW AGROSCIENCES LLC 2011-04-20 CN disclosed
US-20080255233-A1 Isomeric mixtures of dinitro-octylphenyl esters and synergistic fungicidal mixtures therefrom DOW AGROSCIENCES LLC (US) 2008-10-16 US disclosed
CN-101060780-A Isomeric mixtures of dinitro-octylphenyl esters and synergistic fungicidal mixtures therefrom DOW AGROSCIENCES LLC (US) 2007-10-24 CN disclosed
EP-1830641-A1 ISOMERIC MIXTURES OF DINITRO-OCTYLPHENYL ESTERS AND SYNERGISTIC FUNGICIDAL MIXTURES THEREFROM Dow AgroSciences LLC (US) 2007-09-12 EP disclosed
WO-2006044460-A1 ISOMERIC MIXTURES OF DINITRO-OCTYLPHENYL ESTERS AND SYNERGISTIC FUNGICIDAL MIXTURES THEREFROM DOW AGROSCIENCES LLC (US) 2006-04-27 WO disclosed