SCHEMBL30425872

SCHEMBL30425872

CCCCc1c([N+](=O)[O-])ccc(O)c1[N+](=O)[O-]

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 3/20 0.45
TRPV1 Q8NER1 1/20 0.41
HPGD P15428 3/20 0.40
TSHR P16473 3/20 0.40
CTSB P07858 2/20 0.40
TP53 P04637 2/20 0.40
SMN1; SMN2 Q16637 2/20 0.40
CYP3A4 P08684 1/20 0.40
HIF1A Q16665 1/20 0.40
CTSH P09668 1/20 0.40
MAPK1 P28482 3/20 0.39
NPC1 O15118 1/20 0.39
HTT P42858 1/20 0.39
RAB9A P51151 1/20 0.39
NPSR1 Q6W5P4 1/20 0.39
ALDH1A1 P00352 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
MAPT P10636 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MCL1 Q07820 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5691196 1.00 GPR35 (0.45) GPR35TRPV1HPGDTSHRCTSB
SCHEMBL1123245 0.88 GPR35 (0.45) GPR35TRPV1HPGDTSHRCTSB
SCHEMBL1963148 0.87 HPGD (0.42) GPR35HPGDTSHRCTSBTP53
SCHEMBL5587187 0.86 HPGD (0.41) GPR35HPGDTSHRCTSBTP53
SCHEMBL1963149 0.84 TRPV1 (0.46) GPR35TRPV1HPGDTSHRTP53
SCHEMBL27513704 0.83 MAPK1 (0.42) GPR35HPGDTSHRCTSBTP53
SCHEMBL28899639 0.82 GPR35 (0.42) GPR35TRPV1HPGDTSHRCTSB
SCHEMBL1854556 0.82 GPR35 (0.42) GPR35TRPV1HPGDTSHRCTSB
SCHEMBL11421422 0.82 GPR35 (0.42) GPR35TRPV1HPGDTSHRCTSB
SCHEMBL5590139 0.81 TYR (0.44) GPR35HPGDTSHRCTSBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116250044-A Systems and methods for measuring, learning, and using emerging properties of complex adaptive systems 埃梅里亚公司 2023-06-09 CN disclosed