Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 2/20 | 0.56 |
| ▸ | TNKS | O95271 | 1/20 | 0.51 |
| ▸ | PRKDC | P78527 | 7/20 | 0.48 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PIM1 | P11309 | 1/20 | 0.36 |
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.36 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.36 |
| ▸ | PIM3 | Q86V86 | 1/20 | 0.36 |
| ▸ | PIM2 | Q9P1W9 | 1/20 | 0.36 |
| ▸ | GSK3B | P49841 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23328760 | 0.92 | ALOX5 (0.49) | ALOX5TNKSPRKDCGGPS1AR | |
| SCHEMBL25543175 | 0.92 | ALOX5 (0.49) | ALOX5TNKSPRKDCGGPS1AR | |
| SCHEMBL13171115 | 0.91 | ALOX5 (0.55) | ALOX5TNKSPRKDCGGPS1AR | |
| SCHEMBL25544170 | 0.91 | ALOX5 (0.48) | ALOX5TNKSPRKDCGGPS1AR | |
| SCHEMBL23328767 | 0.91 | ALOX5 (0.48) | ALOX5TNKSPRKDCGGPS1AR | |
| SCHEMBL25544085 | 0.91 | ALOX5 (0.48) | ALOX5TNKSPRKDCGGPS1AR | |
| SCHEMBL21691488 | 0.91 | ALOX5 (0.54) | ALOX5TNKSPRKDCGGPS1AR | |
| SCHEMBL16016622 | 0.90 | ALOX5 (0.57) | ALOX5TNKSPRKDCGGPS1AR | |
| SCHEMBL25543156 | 0.89 | ALOX5 (0.47) | ALOX5TNKSPRKDCGGPS1AR | |
| SCHEMBL16016593 | 0.89 | ALOX5 (0.56) | ALOX5TNKSPRKDCGGPS1AR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11643414-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-09 | — | — | US | disclosed |
| US-11643414-B2 | Materials for organic electroluminescent devices | MERCK PATENT GMBH (DE) | 2023-05-09 | — | — | US | disclosed |
| EP-3448866-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-06-17 | — | — | EP | disclosed |
| US-20190135814-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2019-05-09 | — | — | US | disclosed |
| WO-2017186760-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2017-11-02 | — | — | WO | disclosed |
| US-9512137-B2 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2016-12-06 | — | — | US | disclosed |
| US-9512137-B2 | Organic electroluminescence device | IDEMITSU KOSAN CO., LTD. (JP) | 2016-12-06 | — | — | US | disclosed |
| US-20120256172-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2012-10-11 | — | — | US | disclosed |
| US-20120256172-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | IDEMITSU KOSAN CO., LTD. (JP) | 2012-10-11 | — | — | US | disclosed |
| EP-1470102-B1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | MERCK SERONO SA (CH) | 2011-05-25 | — | — | EP | disclosed |
| US-7592477-B2 | Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases (PTPs) | LABORATOIRES SERONO SA (CH) | 2009-09-22 | — | — | US | disclosed |
| US-20050124656-A1 | Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases(ptps) | APPLIED RESEARCH SYSTEMS ARS (NL) | 2005-06-09 | — | — | US | disclosed |
| EP-1470102-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | Applied Research Systems ARS Holding N.V. (AN) | 2004-10-27 | — | — | EP | disclosed |
| WO-2003064376-A1 | SUBSTITUTED METHYLENE AMIDE DERIVATIVES AS MODULATORS OF PROTEIN TYROSINE PHOSPHATASES (PTPS) | APPLIED RESEARCH SYSTEMS ARS HOLDING N.V. (AN) | 2003-08-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120256172-A1 | ORGANIC ELECTROLUMINESCENCE DEVICE | SLC25A21, SLC25A11, SLCO4C1 | ALOX5 4545/4885TNKS 3480/4885PRKDC 4029/4885 |
| US-20050124656-A1 | Substituted methylene amide derivatives as modulators of protein tyrosine phosphatases(ptps) | PTPRS, PTPA, PTPMT1 | ALOX5 1837/4885TNKS 2594/4885PRKDC 1994/4885 |
| US-11643414-B2 | Materials for organic electroluminescent devices | SLCO4C1, SLCO2A1, PIEZO1 | ALOX5 1455/4885TNKS 3349/4885PRKDC 4763/4885 |
| US-20190135814-A1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | SLCO4C1, SLCO2A1, PIEZO1 | ALOX5 1763/4885TNKS 2868/4885PRKDC 4760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.