Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AGER | Q15109 | 1/20 | 0.41 |
| ▸ | STAT3 | P40763 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | GBA1 | P04062 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | DHODH | Q02127 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 3/20 | 0.37 |
| ▸ | CA9 | Q16790 | 3/20 | 0.37 |
| ▸ | CA12 | O43570 | 2/20 | 0.37 |
| ▸ | VDR | P11473 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18546850 | 1.00 | AGER (0.41) | AGERSTAT3MAPTMCOLN3GAA | |
| SCHEMBL18546831 | 1.00 | AGER (0.41) | AGERSTAT3MAPTMCOLN3GAA | |
| SCHEMBL2176311 | 0.82 | GAA (0.45) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL4753667 | 0.82 | GAA (0.45) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL4753668 | 0.82 | GAA (0.45) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL777474 | 0.82 | GAA (0.45) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL4757045 | 0.82 | GAA (0.45) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL3317915 | 0.79 | STAT3 (0.44) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL21114440 | 0.79 | GAA (0.42) | STAT3GAAGBA1ALDH1A1CYP3A4 | |
| SCHEMBL21114439 | 0.79 | GAA (0.42) | STAT3GAAGBA1ALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190002394-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | CODY LABORATORIES, INC. | 2019-01-03 | — | — | US | claimed |
| US-10040752-B2 | Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof | CODY LABORATORIES, INC. (US) | 2018-08-07 | — | — | US | claimed |
| EP-3341354-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | Cody Laboratories, Inc. (US) | 2018-07-04 | — | — | EP | claimed |
| WO-2017035224-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | CODY LABORATORIES, INC. (US) | 2017-03-02 | — | — | WO | claimed |
| US-20170057909-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | ALTER DOMUS (US) LLC | 2017-03-02 | — | — | US | claimed |
| US-20190002394-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | CODY LABORATORIES, INC. | 2019-01-03 | — | — | US | disclosed |
| US-10040752-B2 | Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof | CODY LABORATORIES, INC. (US) | 2018-08-07 | — | — | US | disclosed |
| EP-3341354-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | Cody Laboratories, Inc. (US) | 2018-07-04 | — | — | EP | disclosed |
| WO-2017035224-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | CODY LABORATORIES, INC. (US) | 2017-03-02 | — | — | WO | disclosed |
| US-20170057909-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | ALTER DOMUS (US) LLC | 2017-03-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170057909-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | CYP2D6, COMT, AADAT | AGER 4604/4885STAT3 4726/4885MAPT 1028/4885 |
| US-20190002394-A1 | SYNTHESIS OF LEVOMETHADONE HYDROCHLORIDE OR DEXTROMETHADONE HYDROCHLORIDE AND METHODS FOR USE THEREOF | CYP2D6, COMT, AADAT | AGER 4604/4885STAT3 4726/4885MAPT 1028/4885 |
| US-10040752-B2 | Synthesis of levomethadone hydrochloride or dextromethadone hydrochloride and methods for use thereof | CYP2D6, COMT, AADAT | AGER 4604/4885STAT3 4726/4885MAPT 1028/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.